[HTML][HTML] Adiponectin: mechanistic insights and clinical implications

AT Turer, PE Scherer - Diabetologia, 2012 - Springer
Adiponectin is an adipocyte-derived secretory protein that has been very widely studied over
the past 15 years. A multitude of different functions have been attributed to this adipokine. It …

Adiponectin and lipoprotein metabolism

GA Christou, DN Kiortsis - Obesity reviews, 2013 - Wiley Online Library
Adiponectin is secreted by the adipose tissue and it has been shown to be down‐regulated
in states of insulin resistance and in cardiovascular disease. It has also been found to be …

[HTML][HTML] Adiponectin in insulin resistance: lessons from translational research

F Ziemke, CS Mantzoros - The American journal of clinical nutrition, 2010 - Elsevier
Adiponectin is an adipose tissue–secreted endogenous insulin sensitizer, which plays a key
role as a mediator of peroxisome proliferator-activated receptor γ action. Adiponectin alters …

Adiponectin, obesity and atherosclerosis

CJ Behre - Scandinavian journal of clinical and laboratory …, 2007 - Taylor & Francis
The circulating protein adiponectin has been the subject of immense interest ever since it
was first discovered in the mid‐1990s. The protein is uniquely produced and secreted by …

[HTML][HTML] Adiponectin receptor as a key player in healthy longevity and obesity-related diseases

T Yamauchi, T Kadowaki - Cell metabolism, 2013 - cell.com
Adiponectin is a fat-derived hormone whose reduction plays central roles in obesity-linked
diseases including insulin resistance/type 2 diabetes and atherosclerosis. The cloning of …

[HTML][HTML] Adiponectin: Probe of the molecular paradigm associating diabetes and obesity

K Ghoshal, M Bhattacharyya - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Type 2 diabetes is an emerging health challenge all over the world as a result of
urbanization, high prevalence of obesity, sedentary lifestyle and other stress related factors …

Pathophysiological significance of adiponectin

M Nishida, T Funahashi, I Shimomura - Medical molecular morphology, 2007 - Springer
Adipose tissue, which classically has been considered as an energy-storing organ, is now
viewed as a massive source of bioactive substances such as leptin, tumor necrosis factor …

[HTML][HTML] The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS

T Kadowaki, T Yamauchi, N Kubota - FEBS letters, 2008 - Elsevier
Adiponectin is an abundantly expressed adipokine in adipose tissue and has direct insulin
sensitizing activity. A decrease in the circulating levels of adiponectin by interactions …

Adiponectin: a key fat-derived molecule regulating inflammation

H Tilg, AM Wolf - Expert opinion on therapeutic targets, 2005 - Taylor & Francis
Adiponectin is the abundant adipocyte-derived protein with well-established anti-
atherogenic and insulin-sensitising properties. Besides these well characterised biological …

Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet

S Otabe, X Yuan, T Fukutani, N Wada… - American Journal …, 2007 - journals.physiology.org
Adiponectin, a physiologically active polypeptide secreted by adipocytes, shows insulin-
sensitizing, anti-inflammatory, and antiatherogenic properties in rodents and humans. To …