Adiponectin circulates in blood in multiple isoforms. High molecular weight (HMW)
adiponectin is thought to be most biologically active and promotes glucose uptake, insulin …

Adiponectin regulates energy homeostasis through the modulation of glucose and fatty acid
metabolism in peripheral tissues. However, its central effect on energy balance remains …

Insulin resistance and its dreaded consequence, type 2 diabetes, are major causes of
atherosclerosis. Adiponectin is an adipose-specific plasma protein that possesses anti …

Under disease conditions including obesity (insulin resistance) and diabetes, dysregulation
of adipokines such as tumor necrosis factor (TNF)-α, leptin, resistin, and adiponectin …

Adiponectin is an adipokine with profound antidiabetic and antiatherogenic effects.
Circulating adiponectin concentrations are higher in women than in men. In order to study …

Adiponectin is a major adipocyte-secreted adipokine abundantly present in the circulation
as three distinct oligomeric complexes. In addition to its role as an insulin sensitizer …

The increased prevalence of obesity has mandated extensive research focused on
mechanisms responsible for associated clinical complications. Emerging from the focus on …

Adiponectin is an adipocyte‐derived hormone that was discovered in 1995. Unlike leptin,
which was identified around the same time, the clinical relevance of adiponectin remained …

Adipose tissue is a hormonally active tissue, producing adipocytokines which may influence
activity of other tissues. Adiponectin, abundantly present in the plasma increases insulin …

The relationship between insulin action and control of the adipocyte-derived factor
adiponectin was studied in age-and weight-matched obese individuals with type 2 diabetes …