High adiponectin concentrations are associated with the metabolically healthy obese phenotype

CA Aguilar-Salinas, EG García, L Robles… - The Journal of …, 2008 - academic.oup.com
Context: In the ob/ob mice, keeping adiponectin concentrations in the physiological range
(through overexpression of this gene in the adipose tissue) results in expansion of fat mass …

Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein

H Nishizawa, I Shimomura, K Kishida, N Maeda… - Diabetes, 2002 - Am Diabetes Assoc
Adiponectin, an adipose-specific secretory protein, exhibits antidiabetic and antiatherogenic
properties. In the present study, we examined the effects of sex hormones on the regulation …

[HTML][HTML] Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges

X Lei, S Qiu, G Yang, Q Wu - Genes & Diseases, 2023 - Elsevier
Metabolic cardiovascular diseases have become a global health concern, and some of their
risk factors are linked to several metabolic disorders. They are the leading causes of death …

Adiponectin and cardiovascular disease

R Shibata, N Ouchi, T Murohara - Circulation Journal, 2009 - jstage.jst.go.jp
Obesity is strongly associated with metabolic and cardiovascular disorders. Adiponectin is
an adipose-derived plasma protein that is downregulated in subjects with obesity-related …

Protective role of adiponectin in cardiovascular disease

R Shibata, T Murohara, N Ouchi - Current medicinal chemistry, 2012 - ingentaconnect.com
This review focuses on the recent findings that adiponectin plays a significant role of in
cardiovascular diseases. Adipose tissue functions as an endocrine organ by secreting …

Adiponectin, an unlocking adipocytokine

Y Sun, K Xun, C Wang, H Zhao, H Bi… - Cardiovascular …, 2009 - Wiley Online Library
A large number of studies revealed that adiponectin, a protein secreted specifically by
adipose tissue, exhibits antiinflammatory, antiatherogenic, and antidiabetic properties. This …

[PDF][PDF] Adiponectin: more than just another fat cell hormone?

M Chandran, SA Phillips, T Ciaraldi, RR Henry - Diabetes care, 2003 - Citeseer
Recent research has shown that adi-pose tissue is not simply an inert storage depot for
lipids but is also an important endocrine organ that plays a key role in the integration of …

Adiponectin: a biomarker of obesity-induced insulin resistance in adipose tissue and beyond

JY Lu, KC Huang, LC Chang, YS Huang… - Journal of biomedical …, 2008 - Springer
Adiponectin is one of the most thoroughly studied adipocytokines. Low plasma levels of
adiponectin are found to associate with obesity, metabolic syndrome, diabetes and many …

Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes

AM Bodles, A Banga, N Rasouli… - American Journal …, 2006 - journals.physiology.org
Adiponectin is an adipocyte-derived serum protein that plays important roles in energy
homeostasis, obesity, and insulin sensitivity. Using sucrose gradients and Western blotting …

Adiponectin and cardiovascular disease: state of the art?

PE Szmitko, H Teoh, DJ Stewart… - American Journal of …, 2007 - journals.physiology.org
The cardiometabolic syndrome, associated with increased cardiovascular disease risk in the
industrialized world, is estimated to affect one in four adults. Although the mechanisms …