Regulation of mitochondrial dynamics by dynamin-related protein-1 in acute cardiorenal syndrome
M Sumida, K Doi, E Ogasawara… - Journal of the …, 2015 - journals.lww.com
Experimental evidence has clarified distant organ dysfunctions induced by AKI. Crosstalk
between the kidney and heart, which has been recognized recently as cardiorenal …
between the kidney and heart, which has been recognized recently as cardiorenal …
Sirt3 attenuates post-infarction cardiac injury via inhibiting mitochondrial fission and normalization of AMPK-Drp1 pathways
J Liu, W Yan, X Zhao, Q Jia, J Wang, H Zhang, C Liu… - Cellular signalling, 2019 - Elsevier
Mitochondrial damage is involved in the pathogenesis of post-infarction cardiac injury.
However, the upstream regulators of mitochondrial damage have not yet been identified …
However, the upstream regulators of mitochondrial damage have not yet been identified …
Vagal nerve stimulation improves mitochondrial dynamics via an M3 receptor/CaMKKβ/AMPK pathway in isoproterenol‐induced myocardial ischaemia
RQ Xue, L Sun, XJ Yu, DL Li… - Journal of Cellular and …, 2017 - Wiley Online Library
Mitochondrial dynamics—fission and fusion—are associated with ischaemic heart disease
(IHD). This study explored the protective effect of vagal nerve stimulation (VNS) against …
(IHD). This study explored the protective effect of vagal nerve stimulation (VNS) against …
Inhibition of Drp1 attenuates mitochondrial damage and myocardial injury in Coxsackievirus B3 induced myocarditis
L Lin, M Zhang, R Yan, H Shan, J Diao, J Wei - … and biophysical research …, 2017 - Elsevier
Viral myocarditis (VMC) is closely related to apoptosis, oxidative stress, innate immunity, and
energy metabolism, which are all linked to mitochondrial dysfunction. A close nexus …
energy metabolism, which are all linked to mitochondrial dysfunction. A close nexus …
[Retracted] Novel Insights into the Molecular Features and Regulatory Mechanisms of Mitochondrial Dynamic Disorder in the Pathogenesis of Cardiovascular Disease
Y Tan, F Xia, L Li, X Peng, W Liu… - Oxidative Medicine …, 2021 - Wiley Online Library
Mitochondria maintain mitochondrial homeostasis through continuous fusion and fission,
that is, mitochondrial dynamics, which is precisely mediated by mitochondrial fission and …
that is, mitochondrial dynamics, which is precisely mediated by mitochondrial fission and …
[HTML][HTML] Targeting mitochondrial fission using Mdivi-1 in a clinically relevant large animal model of acute myocardial infarction: a pilot study
SB Ong, XY Kwek, K Katwadi… - International journal of …, 2019 - mdpi.com
Background: New treatments are needed to reduce myocardial infarct size (MI) and prevent
heart failure (HF) following acute myocardial infarction (AMI), which are the leading causes …
heart failure (HF) following acute myocardial infarction (AMI), which are the leading causes …
Mitochondrial fission–a drug target for cytoprotection or cytodestruction?
Mitochondria are morphologically dynamic organelles constantly undergoing processes of
fission and fusion that maintain integrity and bioenergetics of the organelle: these processes …
fission and fusion that maintain integrity and bioenergetics of the organelle: these processes …
The role of mitochondrial fission in cardiovascular health and disease
JM Quiles, ÅB Gustafsson - Nature Reviews Cardiology, 2022 - nature.com
Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …
Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death
KN Papanicolaou, GA Ngoh… - American Journal …, 2012 - journals.physiology.org
Molecular studies examining the impact of mitochondrial morphology on the mammalian
heart have previously focused on dynamin related protein-1 (Drp-1) and mitofusin-2 (Mfn-2) …
heart have previously focused on dynamin related protein-1 (Drp-1) and mitofusin-2 (Mfn-2) …
[HTML][HTML] DPP4 Deficiency Exerts Protective Effect against H2O2 Induced Oxidative Stress in Isolated Cardiomyocytes
HC Ku, WP Chen, MJ Su - PLoS One, 2013 - journals.plos.org
Apart from the antihyperglycemic effects, DPP4 inhibitors and GLP-1 molecules are involved
in the preservation of cardiac functions. We have demonstrated that DPP4-deficient rats …
in the preservation of cardiac functions. We have demonstrated that DPP4-deficient rats …