Many sources purport that antidepressants have a delayed onset of action, measured in
weeks rather than days. Recent data using weekly or daily mood ratings demonstrate that …

Objective: To review the proposition that antidepressants have a delayed onset of action by
employing measurement and analytic strategies that overcome problems confounding …

In standard drug trials comparing antidepressants with placebo, a period of typically 3 weeks
is required before formal statistical significance between treatments is achieved. This delay …

Antidepressant medications generally are considered to have a delayed onset of action;
however, recent evidence is beginning to challenge this conventional wisdom. Meta …

Objectives: It has long been thought that there is a delay of several weeks before a true
antidepressant effect occurs, although this theory has increasingly come into question. The …

Background: For years, investigators have tried to determine the speed of onset of
antidepressant drugs. Claims that particular drugs may produce a faster response in patients …

The onset of action of antidepressant drugs was investigated on the basis of two
independent, multicenter, double-blind studies, comparing amitriptyline (N= 120) …

Although various published clinical studies have suggested that some antidepressants may
have a more rapid onset of therapeutic effect than others, none of these trials was …

Antidepressants clearly benefit patients suffering from depressive disorders, but the extent to
which they are better than psychological treatments, and in which kinds or types of …

The onset of action of antidepressant drugs was investigated on the basis of two
independent multicenter, double-blind efficacy studies comparing amitriptyline (n= 120) …