The mitochondria of the oocyte are a prominent source of energy metabolism as well as
mitochondrial DNA that will later populate the cells of the offspring. Recent discoveries …

This review examines the place of mitochondria in the life cycle through oogenesis,
ovulation and early embryogenesis. Mitochondria are semi-autonomous organelles …

Mitochondrial dysfunction is widely implicated in various human diseases, through
mechanisms that go beyond mitochondria's well-established role in energy generation …

Mitochondrial biology plays an important role in the reproductive process, with influence on
germ cell development and quality as well as embryonic development and reproductive …

The role of mitochondria in the establishment of developmental competence for the
preimplantation mammalian embryo is an area of growing interest for researchers …

Genetic defects of the mitochondrial genome can be especially devastating to patients;
moreover, attention on human mitochondrial disorders has grown remarkably in recent …

Mitochondria are energy provider organelles in eukaryotic cells that contain their own
specific genome. This review addresses structural and functional properties of mitochondria …

Contrasting the equal contribution of nuclear genetic material from maternal and paternal
sources to offspring, passage of mitochondria, and thus mitochondrial DNA (mtDNA), is …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

Many diseases have their origins at the time of fertilization when the oocyte and sperm unite.
These diseases can arise from the subsequent transmission of genetic and epigenetic …