The establishment of NJS strain mouse as atherosclerosis model, including the origin,
breeding objectives, breeding method, reproductive system, care and management were …

Inbred NJS mouse strain was bred by using continuous brother-sister mating and directive
breeding on the common diet with serum cholesterol at 70 days as breeding index. Acording …

抄録 By successive selective brother-sister breeding of crossbred hybrid male TC-C and
female TC, both developed by crossing severely hypertensive rats (M-SHRSP) with …

Coronary artery disease has a significant genetic predisposition, which mainly results from
atherosclerosis. Miniature pig is an excellent model to investigate atherosclerosis. This study …

Coronary artery disease has a significant genetic predisposition, which mainly results from
atherosclerosis. Miniature pig is an excellent model to investigate atherosclerosis. This study …

To identify the genetic factors affecting susceptibility to atherosclerosis, we studied the
inheritance of plasma total cholesterol (TC) and HDL cholesterol (HDL-C) concentrations …

Animal models of human diseases play an extremely important role in biomedical research.
Among them, mice are widely used animal models for translational research, especially …

抄録 Using hybrid offspring developed through crossbreeding severely spontaneously
hypertensive rats (M-SHRSP) with spontaneously hypercholesterolemic rats (SHC), it was …

Materials and Methods Selective brother-sister breeding was performed using mainly
offspring with high plasma cholesterol. Data collected on each generation have included …

A collection of these macrophage foam cells makes up the first grossly visible lesion, called
the fatty streak. The next stage of lesion development is called the intermediate fibrous …