Fenofibrate reduces fasting and postprandial inflammatory responses among hypertriglyceridemia patients with the metabolic syndrome

RS Rosenson, AL Huskin, DA Wolff, IB Helenowski… - Atherosclerosis, 2008 - Elsevier
OBJECTIVE: To examine the effects of fenofibrate (160mg/d) therapy on fasting and
postprandial cytokine production in subjects with metabolic syndrome and …

Fenofibrate therapy ameliorates fasting and postprandial lipoproteinemia, oxidative stress, and the inflammatory response in subjects with hypertriglyceridemia and …

RS Rosenson, DA Wolff, AL Huskin… - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—The aim of this study was to determine the effects of fenofibrate (160 mg/day)
on fasting and postprandial lipoproteins, oxidized fatty acids, and inflammatory mediators in …

Effect of fenofibrate on serum inflammatory markers in patients with high triglyceride values

V Tsimihodimos, A Kostoula… - Journal of …, 2004 - journals.sagepub.com
Background: Atherosclerosis is the leading cause of death in developed countries. Although
the mechanisms that underlie this process are not well defined, it has been proposed that …

Severe hypertriglyceridemia with insulin resistance is associated with systemic inflammation: reversal with bezafibrate therapy in a randomized controlled trial

IJ Jonkers, MF Mohrschladt, RG Westendorp… - The American journal of …, 2002 - Elsevier
PURPOSE: To determine whether hypertriglyceridemia is associated with systemic
inflammation, which may contribute to the increased cardiovascular risk in patients who …

Metabolic and monocyte-suppressing actions of fenofibrate in patients with mixed dyslipidemia and early glucose metabolism disturbances

R Krysiak, A Stachura-Kułach, B Okopień - Pharmacological Reports, 2010 - Springer
The aim of this study was to compare the action of fenofibrate on monocyte cytokine release
between patients with isolated mixed dyslipidemia and dyslipidemia coexisting …

Fenofibrate reduces systemic inflammation markers independent of its effects on lipid and glucose metabolism in patients with the metabolic syndrome

R Belfort, R Berria, J Cornell… - The Journal of Clinical …, 2010 - academic.oup.com
Context: Fenofibrate is a peroxisome proliferator-activated receptor α agonist widely used in
clinical practice, but its mechanism of action is incompletely understood. Objective: The aim …

Decrease in inflammatory cardiovascular risk markers in hyperlipidemic diabetic patients treated with fenofibrate

TJ Wu, HY Ou, CW Chou, SH Hsiao… - Annals of Clinical & …, 2007 - Assoc Clin Scientists
The goal was to investigate the effect of micronized fenofibrate, a hypolipidemic drug, on
inflammatory markers and proinsulin in patients with type 2 diabetes who had …

Effects of fenofibrate on endothelial function and cell adhesion molecules during post‐prandial lipemia in hypertriglyceridemia

S Marchesi, G Lupattelli, R Lombardini… - Journal of clinical …, 2003 - Wiley Online Library
Background: Fasting and post‐prandial hypertriglyceridemia have been associated with
endothelial dysfunction. Objective: To investigate the effects of a 3‐month treatment with …

Effects of fenofibrate therapy on circulating adipocytokines in patients with primary hypertriglyceridemia

KK Koh, MJ Quon, S Lim, Y Lee, I Sakuma, YH Lee… - Atherosclerosis, 2011 - Elsevier
BACKGROUND: We investigated effects of fenofibrate therapy on endothelial dysfunction
and adipocytokine profiles. METHODS: A randomized, single-blind, placebo-controlled …

Monocyte‐suppressing effect of bezafibrate but not omega‐3 fatty acids in patients with isolated hypertriglyceridaemia

R Krysiak, A Gdula‐Dymek… - Basic & clinical …, 2011 - Wiley Online Library
Fibrates and omega‐3 fatty acids have been used for many years in the treatment of
increased triglyceride levels. Unfortunately, pleiotropic effects of these agents in patients …