Improved survival from intracavitary photodynamic therapy of rat glioma

YJD Walstad, JT Brown… - Photochemistry and …, 1992 - Wiley Online Library
The effectiveness of intratumoral photoradiation in photodynamic therapy (PDT) using a
polyporphyrin photosensitizer was studied in the RT‐2 rat glioma model. One week after …

Damage to tumour and brain by interstitial photodynamic therapy in the 9L rat tumour model comparing intravenous and intratumoral administration of the …

KM Hebeda, W Kamphorst, H Sterenborg… - Acta …, 1998 - Springer
In the 9L rat brain tumour model the damage to tumour and normal brain by photodynamic
therapy after intratumoural photosensitizer administration (intratumoural PDT) was studied …

Photodynamic therapy of malignant brain tumours: a phase III trial

H Kostron, E Fritsch, V Grunert - British journal of neurosurgery, 1988 - Taylor & Francis
Twenty patients bearing malignant brain tumours (18 glioblastoma multiforme, one
malignant meningioma, one melanoma metastasis) were treated 25 times with …

Modulation of light delivery in photodynamic therapy of brain tumours

SH Tudge, AH Kaye, JS Hill - Journal of clinical neuroscience, 1999 - Elsevier
This study was performed to determine whether modulation of light delivery could improve
tumour kill in photodynamic therapy (PDT) of brain tumours, as optimal dosimetry has not …

Photodynamic therapy for intracranial neoplasms: Literature review and institutional experience

TC Origitano, MJ Caron… - Molecular and chemical …, 1994 - Springer
Primary malignant glial neoplasms of the central nervous system have a dismal 2-yr
prognosis. An innovative approach to these formidable lesions is photodynamic therapy that …

Repetitive photodynamic therapy of malignant brain tumors

H Hirschberg, DR Sorensen… - Journal of …, 2006 - dl.begellhouse.com
The probability of achieving local control with current single-shot, intraoperative
photodynamic therapy (PDT) treatments of intracerebral gliomas seems improbable due to …

[HTML][HTML] Current Photodynamic Therapy for Glioma Treatment: An Update

D Aebisher, A Przygórzewska, A Myśliwiec… - Biomedicines, 2024 - mdpi.com
Research on the development of photodynamic therapy for the treatment of brain tumors has
shown promise in the treatment of this highly aggressive form of brain cancer. Analysis of …

Instrumentation and light dosimetry for intra-operative photodynamic therapy (PDT) of malignant brain tumours

BC Wilson, PJ Muller, JC Yanch - Physics in Medicine & Biology, 1986 - iopscience.iop.org
A technique is described for uniform light irradiation of the tumour cavity after radical subtotal
malignant brain tumour resection in patients whose tumours have been photosensitised by …

Experimental research photodynamic effects in perifocal, oedematous brain tissue

C Goetz, A Hasan, W Stummer, A Heimann… - Acta …, 2002 - Springer
Summary. Background: Photodynamic therapy (PDT) has been under discussion as
additional treatment option for malignant gliomas. However, damage not only to tumour …

Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model

E Angell-Petersen, S Spetalen, SJ Madsen… - Journal of …, 2006 - thejns.org
Object Failure of treatment for high-grade gliomas is usually due to local recurrence at the
site of resection, indicating that a more aggressive local therapy could be beneficial …