Chemopreventive and growth inhibitory effects of selenium.

PR Harrison, J Lanfear, L Wu, J Fleming… - Biomedical and …, 1997 - europepmc.org
There is very convincing evidence that a high dietary level of selenium substantially reduces
the incidence of a wide variety of animal cancers. The human epidemiological evidence is …

Effect of selenium and molybdenum on methylbenzylnitrosamine-induced esophageal lesions and tissue trace metals in the rat

JD Bogden, HR Chung, FW Kemp, K Holding… - The Journal of …, 1986 - Elsevier
Thirty-six weanling male Sprague-Dawley rats were randomly assigned to one of four
treatment groups: 1) SE rats received 4.0 ppm selenium as sodium selenite in drinking water …

Dietary selenium-and benzo [a] pyrene-induced respiratory tract tumours in hamsters

RB Beems - Carcinogenesis, 1986 - academic.oup.com
The modifying effect of selenium as sodium selenite on chemically induced respiratory tract
tumours was tested in Syrian golden hamsters. Groups of 40 hamsters per sex (controls 60 …

Enhancement of mammary tumorigenesis by dietary selenium deficiency in rats with a high polyunsaturated fat intake

C Ip, DK Sinha - Cancer Research, 1981 - AACR
The effect of selenium depletion on mammary tumorigenesis following dimethylbenz [a]
anthracene administration was examined in female Sprague-Dawley rats that were fed …

Selenium and cabbage and colon carcinogenesis in mice

NJ Temple, TK Basu - Journal of the National Cancer Institute, 1987 - academic.oup.com
The influence of dietary selenium and cabbage on the formation of colon tumors in female
Swiss mice treated with 1, 2-dimethylhydrazine [(DMH) CAS: 540-73-8] was reported. Mice …

Prophylaxis of mammary neoplasia by selenium supplementation in the initiation and promotion phases of chemical carcinogenesis

C Ip - Cancer research, 1981 - AACR
The present study was designed to determine the chemopreventive effect of dietary
selenium supplementation in the initiation or promotion phase of 7, 12-dimethylbenz [a] …

Selenium deficiency and detoxication functions in the rat: short-term effects of cadmium.

U Olsson - Drug-nutrient interactions, 1986 - europepmc.org
Weanling rats were fed a Torula yeast-based selenium-deficient diet with or without
supplementation of sodium selenite (0.2 ppm selenium) in the drinking water. After 5-6 …

Effect of dietary selenium on tumor induction by an oncogenic virus

JH Exon, LD Koller, SC Elliott - Clinical toxicology, 1976 - Taylor & Francis
The relationship of selenium to cancer is obscure. Early studies associated selenium
compounds with neoplasia in aged rats [7, 161, but experiments performed later did not …

Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats

C Ip - Journal of the National Cancer Institute, 1986 - academic.oup.com
The objectives of this study were a) to compare the efficacy of inorganic and organic
selenium compounds in protecting against mammary tumorigenesis induced by 7, 12 …

The effect of four chemical forms of selenium on mammary tumor incidence in BALB/c female mice treated with 7-12-dimethylbenz [a] anthracene

HW Lane, P Teer, J Dukes, J Johnson, MT White - Cancer letters, 1990 - Elsevier
The study was conducted to determine the effect of four forms of selenium on inhibition of
DMBA-induced mammary tumors. BALB/c virgin female mice were fed the AIN-76 diet …