Selenium and tellurium in rats: effect on growth, survival and tumors

HA Schroeder, M Mitchener - The Journal of Nutrition, 1971 - Elsevier
To evaluate the innate toxic effects of selenate, selenite and tellurite, 313 rats were given 2
ppm selenium or tellurium as these compounds in drinking water from the time of weaning …

The effect of four chemical forms of selenium on mammary tumor incidence in BALB/c female mice treated with 7-12-dimethylbenz [a] anthracene

HW Lane, P Teer, J Dukes, J Johnson, MT White - Cancer letters, 1990 - Elsevier
The study was conducted to determine the effect of four forms of selenium on inhibition of
DMBA-induced mammary tumors. BALB/c virgin female mice were fed the AIN-76 diet …

Toxicity of nutritionally available selenium compounds in primary and transformed hepatocytes

M Weiller, M Latta, M Kresse, R Lucas, A Wendel - Toxicology, 2004 - Elsevier
The essential trace element selenium is also toxic at low doses. Since supplementation of
selenium is discussed as cancer prophylaxis, we investigated whether or not bioavailable …

Effect of deficiencies of selenium and vitamin E alone or in combination on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea

HJ Thompson - Carcinogenesis, 1991 - academic.oup.com
Experiments were conducted to determine the dietary levels of selenium and vitamin E that
could be fed chronically to induce a deficiency of one or both nutrients. It was observed that …

Inhibition by selenium of intrahepatic cholangiocarcinoma induction in Syrian Golden hamsters by N'‐nitrosobis(2‐oxopropyl)amine

Y Kise, M Yamamura, M Kogata, M Nakagawa… - 1991 - Taylor & Francis
The effects of selenium supplementation on induction of cholangiocarcinomas and related
precancerous lesions in female Syrian Golden hamsters by N'‐nitrosobis (2‐oxopropyl) …

The LEC rat possesses reduced hepatic selenium, contributing to the severity of spontaneous hepatitis and sensitivity to carcinogenesis

JS Downey, CD Bingle, S Cottrell, N Ward… - Biochemical and …, 1998 - Elsevier
The hepatic concentrations of copper, zinc, magnesium, calcium, and selenium were
measured in LEC rats, which develop a spontaneous form of hepatitis at 3-4 months of age …

Attenuation of the anticarcinogenic action of selenium by vitamin E deficiency.

C Ip - Cancer letters, 1985 - europepmc.org
The present study showed that in the dimethylbenz [a] anthracene-induced mammary tumor
model in rats, the anticarcinogenic efficacy of selenium was much attenuated when the …

Anticarcinogenic effect of selenium in rats treated with dimethylbenz [a] anthracene and fed different levels and types of fat

C Ip, D Sinha - Carcinogenesis, 1981 - academic.oup.com
The present investigation reports the effect of selenium supplementation on 7, 12-
dimethylbenz [a] anthracene (DMBA)-induced mammary carcinogenesis in rats fed either a …

Effects of dietary selenium compounds on benzo (a)-pyrene-induced forestomach tumours and whole-blood glutathione peroxidase activities in C3H mice.

K Bergman, P Slanina - Anticancer Research, 1986 - europepmc.org
Selenium (Se) compounds have shown an inhibitory effect on chemically induced tumours
in several laboratory models and there is an inverse epidemiological relationship between …

Mechanisms of selenium inhibition of tumorigenesis

D Medina - Journal of the American College of Toxicology, 1986 - journals.sagepub.com
INTRODUCTION s IP HAS DISCUSSED,(') selenium supplementation inhibits tumorigenesis
in a variety of organs A and species and under different dietary conditions. The majority of …