[HTML][HTML] Natural acetylcholinesterase inhibitors: A multi-targeted therapeutic potential in Alzheimer's disease

K Gajendra, GK Pratap, DV Poornima… - European Journal of …, 2024 - Elsevier
Abstract Alzheimer's disease (AD), the main dementia type accounting for over 70% of the
entire dementia population, progressive decline in memory and executive function. AD …

[HTML][HTML] Advances on plant extracts and phytocompounds with acetylcholinesterase inhibition activity for possible treatment of Alzheimer's disease

R Taqui, M Debnath, S Ahmed, A Ghosh - Phytomedicine plus, 2022 - Elsevier
Background Alzheimer's disease (AD) is a neurodegenerative disease caused by the
formation of amyloid-beta (Aβ) plaques and neurofibrillary tangles. Acetylcholinesterase …

[HTML][HTML] Potential therapeutic natural products against Alzheimer's disease with Reference of Acetylcholinesterase

S Ahmed, ST Khan, MK Zargaham, AU Khan… - Biomedicine & …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), is the most common type of dementia primarily affecting
the later years of life. Its prevalence is likely to increase in any aging population and will be a …

Potent acetylcholinesterase inhibitors: potential drugs for Alzheimer's disease

H Akıncıoğlu, İ Gülçin - Mini reviews in medicinal chemistry, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is one of the cognitive or memory-related impairments occurring
with advancing age. Since its exact mechanism is not known, the full therapy has still not …

Acetylcholinesterase inhibitory agents in plants and their application to dementia: Alzheimer's disease

WO Castillo-Ordoñez, N Cajas-Salazar - Diagnosis and Management in …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common type of dementia worldwide. It is a
progressive neurodegenerative disorder that gradually destroys the patient's memory and …

Flavonoids as acetylcholinesterase inhibitors

I Uriarte-Pueyo, MI Calvo - Current medicinal chemistry, 2011 - ingentaconnect.com
Flavonoids are new promising potential natural compounds for treating Alzheimer's disease
(AD). Actually most promising drugs for symptomatic treatment of AD are …

Acetylcholinesterase inhibitors as Alzheimer therapy: from nerve toxins to neuroprotection

M Singh, M Kaur, H Kukreja, R Chugh, O Silakari… - European journal of …, 2013 - Elsevier
Acetylcholinesterase is a member of the α/β hydrolase protein super family, with a significant
role in acetylcholine-mediated neurotransmission. Research in the modulators of AChEs …

Acetylcholinesterase enzyme inhibitor molecules with therapeutic potential for alzheimer's disease

B Sivaraman, V Raji, BA Velmurugan… - CNS & Neurological …, 2022 - ingentaconnect.com
Acetylcholinesterase (AchE), hydrolase enzyme, regulates the hydrolysis of acetylcholine
neurotransmitter in the neurons. AchE is found majorly in the central nervous system at the …

Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment

A Musial, M Bajda, B Malawska - Current medicinal chemistry, 2007 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the central
nervous system (CNS) which is the most common cause of dementia in the elderly. It is …

Highly significant scaffolds to design and synthesis cholinesterase inhibitors as anti-alzheimer agents

Y Pourshojaei, K Eskandari… - Mini Reviews in …, 2019 - ingentaconnect.com
Alzheimer, a progressive disease, is a common term for memory loss which interferes with
daily life through severe influence on cognitive abilities. Based on the cholinergic …