Decellularized skin substitutes can be proposed to repair all type of cutaneous defects and
are an important and popular tool in reconstructive medicine. This chapter gives readers an …

Biomaterials science encompasses elements of medicine, biology, chemistry, materials, and
tissue engineering. They are engineered to interact with biological systems to treat …

The skin is the largest organ in the body, fulfilling a variety of functions and acting as a
barrier for internal organs against external insults. As for extensive or irreversible damage …

We standardized the protocol for the development of acellular dermal matrix from rabbit skin.
Acellular dermal matrices are composed of extracellular matrix (ECM) and are typically …

Background: Over recent decades, scientists and surgeons have collaborated to develop
various bioengineered and synthetic products as an alternative to skin grafts. Despite the …

One of the major health concerns, worldwide, is the incidence of chronic wounds and their
treatment costs. The conventional treatment for wound healing involves skin grafting …

The skin is the largest organ of the body, and its integrity is vital to survival. Significant skin
loss, as seen in some thermal injuries, is associated with a high morbidity and mortality …

Skin substitutes are heterogeneous group of biological and/or synthetic elements that
enable the temporary or permanent occlusion of wounds. Although dermal substitutes can …

A matrix derived from natural tissue functions as a highly biocompatible and versatile
scaffold for tissue engineering applications. It can act as a supportive construct that provides …

The major applications of tissue-engineered skin substitutes are in promoting the healing of
acute and chronic wounds. Several approaches have been taken by commercial companies …