Preconditioning protects against systemic disorders associated with hepatic ischemia-reperfusion through blockade of tumor necrosis factor–induced P-selectin up …

C Peralta, L Fernández, J Panés, N Prats, M Sans… - Hepatology, 2001 - Elsevier
Previous studies indicate that ischemic preconditioning protects against lung injury resulting
from hepatic ischemia-reperfusion (I/R) through inhibition of tumor necrosis factor (TNF) …

Early stress protein gene expression in a human model of ischemic preconditioning

A Patel, MCG van de Poll, JWM Greve… - …, 2004 - journals.lww.com
Intermittent clamping of the porta hepatis (PHC) is commonly performed during liver surgery
to reduce blood loss and has been reported to precondition livers resulting in improved …

[PDF][PDF] Ischemic preconditioning of the liver: a few perspectives from the bench to bedside translation

KK Desai, GS Dikdan, A Shareef… - Liver …, 2008 - Wiley Online Library
Utilization of ischemic preconditioning to ameliorate ischemia/reperfusion injury has been
extensively studied in various organs and species for the past two decades. While hepatic …

Hepatic ischemic preconditioning in mice is associated with activation of NF-κB, p38 kinase, and cell cycle entry

N Teoh, AD Pena, G Farrell - Hepatology, 2002 - journals.lww.com
A brief period of hepatic ischemia protects the liver against subsequent ischemia-
reperfusion (IR) injury, but the mechanism of such preconditioning is poorly understood. We …

Microvascular dysfunction induced by reperfusion injury and protective effect of ischemic preconditioning

JC Cutrn, MG Perrelli, B Cavalieri, C Peralta… - Free Radical Biology …, 2002 - Elsevier
Hepatic ischemia/reperfusion injury has immediate and deleterious effects on the outcome
of patients after liver surgery. The precise mechanisms leading to the damage have not …

Effects of ischemic preconditioning on regenerative capacity of hepatocyte in the ischemically damaged rat livers

A Bedirli, M Kerem, H Pasaoglu, O Erdem… - Journal of Surgical …, 2005 - Elsevier
BACKGROUND: Liver regeneration after partial hepatectomy is regulated by several factors
that activate or inhibit hepatocyte proliferation. A short period of ischemia-reperfusion (IR) …

An evaluation of ischaemic preconditioning as a method of reducing ischaemia reperfusion injury in liver surgery and transplantation

FP Robertson, BJ Fuller, BR Davidson - Journal of clinical medicine, 2017 - mdpi.com
Liver Ischaemia Reperfusion (IR) injury is a major cause of post-operative liver dysfunction,
morbidity and mortality following liver resection surgery and transplantation. There are no …

[PDF][PDF] Impact of hyperthermic preconditioning on postischemic hepatic microcirculatory disturbances in an isolated perfusion model of the rat liver

H Terajima, G Enders, A Thiaener, C Hammer… - …, 2000 - Wiley Online Library
Sublethal hyperthermia and the following recovery from this heat exposure, referred to as
hyperthermic preconditioning, elicits a transient state of tolerance to oxidative insults through …

[PDF][PDF] Ischemic preconditioning of the murine liver protects through the Akt kinase pathway

K Izuishi, A Tsung, MA Hossain, M Fujiwara… - …, 2006 - Wiley Online Library
Hepatic ischemia‐reperfusion (I/R) injury occurs in the settings of transplantation, trauma,
and elective liver resection. Ischemic preconditioning has been used as a strategy to reduce …

Interleukin-6 is a key mediator of the hepatoprotective and pro-proliferative effects of ischaemic preconditioning in mice

N Teoh, J Field, G Farrell - Journal of hepatology, 2006 - Elsevier
BACKGROUND/AIMS: The biological effects of ischaemic preconditioning include NF-κB
activation, increased TNF synthesis, stimulation of cell cycle entry and hepatoprotection …