Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system
DL Rosin, A Robeva, RL Woodard… - Journal of …, 1998 - Wiley Online Library
The A2A adenosine receptor (A2A‐AR) transcript and radioligand binding sites have a
distinct distribution in rat brain, restricted primarily to the striatum, nucleus accumbens and …
distinct distribution in rat brain, restricted primarily to the striatum, nucleus accumbens and …
Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum
Activation of adenosine A2A receptors (A2AR) has been shown to antagonize the function of
D2 dopaminergic regulation of striatal γ‐aminobutyric acid (GABA)‐ergic output and, thus …
D2 dopaminergic regulation of striatal γ‐aminobutyric acid (GABA)‐ergic output and, thus …
Receptor heteromerization in adenosine A2A receptor signaling: Relevance for striatal function and Parkinson's disease
K Fuxe, LF Agnati, K Jacobsen, J Hillion, M Canals… - Neurology, 2003 - AAN Enterprises
Recently evidence has been presented that adenosine A2A and dopamine D2 receptors
form functional heteromeric receptor complexes as demonstrated in human neuroblastoma …
form functional heteromeric receptor complexes as demonstrated in human neuroblastoma …
Binding of the prototypical adenosine A2A receptor agonist CGS 21680 to the cerebral cortex of adenosine A1 and A2A receptor knockout mice
2‐p‐(2‐carboxyethylphenethylamino‐5′‐ethylcarboxamidoadenosine)(CGS 21680) is
considered the reference compound to study adenosine A2A receptors. However, CGS …
considered the reference compound to study adenosine A2A receptors. However, CGS …
Adenosine A2A receptors and basal ganglia physiology
Adenosine A2A receptors are highly enriched in the basal ganglia system. They are
predominantly expressed in enkephalin-expressing GABAergic striatopallidal neurons and …
predominantly expressed in enkephalin-expressing GABAergic striatopallidal neurons and …
Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders
The interest on targeting adenosine A2A receptors in the realm of psychiatric diseases first
arose based on their tight physical and functional interaction with dopamine D2 receptors …
arose based on their tight physical and functional interaction with dopamine D2 receptors …
Adenosine A2 receptors: selective localization in the human basal ganglia and alterations with disease
MI Martinez-Mir, A Probst, JM Palacios - Neuroscience, 1991 - Elsevier
Adenosine A2 receptors were labeled and visualized by autoradiography in tissue sections
of the human brain using the A2-selective agonist ligand [3 H](2-p-(2-car☐ yethyl) …
of the human brain using the A2-selective agonist ligand [3 H](2-p-(2-car☐ yethyl) …
Binding of the Adenosine A2 Receptor Ligand [3H]CGS 21680 to Human and Rat Brain: Evidence for Multiple Affinity Sites
W Wan, GR Sutherland, JD Geiger - Journal of neurochemistry, 1990 - Wiley Online Library
A new radiolabeled adenosine receptor agonist, 2‐[p‐(2‐carboxyethyl) phenethylamino]‐
5′‐. N‐ethylcarboxamidoadenosine (CGS 21680), apparently specific for high‐affinity …
5′‐. N‐ethylcarboxamidoadenosine (CGS 21680), apparently specific for high‐affinity …
Distribution of adenosine A2 receptor mRNA in the human brain
SN Schiffmann, F Libert, G Vassart… - Neuroscience …, 1991 - Elsevier
The distribution of the messenger RNA coding for the recently cloned adenosine A 2
receptor was studied in the human brain using in situ hybridization histochemistry. A 2 …
receptor was studied in the human brain using in situ hybridization histochemistry. A 2 …
Immunohistochemical detection of A1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and …
SA Rivkees, SL Price, FC Zhou - Brain research, 1995 - Elsevier
Polyclonal antisera were generated against two identical regions of rat and human A1
adenosine receptors using synthetic multiple-antigenic-peptides as immunogens. Western …
adenosine receptors using synthetic multiple-antigenic-peptides as immunogens. Western …