There is now good reason to believe that blockade of the adenosine A 2A receptor could be
of value in the treatment of Parkinson's disease. Peter J. Richardson, Hiroshi Kase and Peter …

The human A3 adenosine receptor was cloned from a striatal cDNA library using a probe
derived from the homologous rat sequence. The cDNA encodes a protein of 318 amino …

Adenosine plays a very significant role in modulating striatal glutamatergic and
dopaminergic neurotransmission. In the present essay we first review the extensive …

A2A Adenosine Receptors from Rat Striatum and Rat Pheochromocytoma PC12 Cells:
Characterization with Radioligand Binding and by Activation of Adenylate Cyclase - PMC …

Basal ganglia processing results from a balanced activation of direct and indirect striatal
efferent pathways, which are controlled by dopamine D1 and D2 receptors, respectively …

Using the sequence conservation in the G protein-coupled receptor superfamily, we have
isolated an adenosine A 1 receptor cDNA from a human hippocampal cDNA library by …

The function of striatal adenosine A 2A receptors (A 2A Rs) is well recognized because of
their high expression levels and the documented antagonistic interaction between A 2A Rs …

When tested under conditions reducing the endogenous production of adenosine (presence
of adenosine deaminase (ADA) 1.6 IU/ml; and deoxyadenosine triphosphate (d-ATP)), and …

Adenosine A2A-dopamine D2 receptor interactions play a very important role in striatal
function. A2A-D2 receptor interactions provide an example of the capabilities of information …

Adenosine A2A and dopamine D2 receptors have been shown previously to form
heteromeric complexes and interact at the level of agonist binding, G protein coupling, and …