When tested under conditions reducing the endogenous production of adenosine (presence
of adenosine deaminase (ADA) 1.6 IU/ml; and deoxyadenosine triphosphate (d-ATP)), and …

The A2AR is largely coexpressed with D2Rs and enkephalin mRNA in the striatum where it
modulates dopaminergic activity. Activation of the A2AR antagonizes D2R-mediated …

Adenosine A2A-dopamine D2 receptor interactions play a very important role in striatal
function. A2A-D2 receptor interactions provide an example of the capabilities of information …

Dopamine D2 receptors (Rs) and adenosine A2ARs are coexpressed on striatopallidal
neurons, where they mediate opposing actions. In agreement with the idea that D2Rs …

The cellular co-expression of adenosine A 2a receptor mRNA and preproenkephalin A (PPE
A) mRNA and A 2a receptor mRNA and prosomatostatin (pSRIF) mRNA in rat striatum was …

ABSTRACT A1 adenosine receptors in the rat prepinform cortex play an important role in the
inhibition of bicuculline methiodide-induced convulsions. In the present study we evaluated …

A novel receptor cDNA was isolated from a human hippocampal cDNA library. The encoded
polypeptide contains structural features consistent with its classification as a G protein …

Monoclonal antibodies were generated against the adenosine A1 receptor (A1R) purified
from rat brain. In immunoblot analyses of purified or partially purified A1R preparations from …

Adenosine regulates many physiological functions through specific cell membrane
receptors. On the basis of pharmacological studies and molecular cloning, four different …

Brain adenosine A2A receptors have recently attracted considerable attention because of
their interaction with the dopaminergic system and as potential targets for Parkinson's …