Direct autoradiographic localization of adenosine A2 receptors in the rat brain using the A2-selective agonist,[3H] CGS 21680

MF Jarvis, M Williams - European journal of pharmacology, 1989 - Elsevier
The regional distribution of adenosine A 2 receptors in the rat brain was determined using
the A 2-selective agonist ligand [3 H](2-p-carboxyethyl) phenylamino)-5′-N …

Adenosine A3 receptors are located in neurons of the rat hippocampus

LV Lopes, N Rebola, PC Pinheiro, PJ Richardson… - …, 2003 - journals.lww.com
Adenosine is a neuromodulator acting mainly via inhibitory A 1 and facilitatory A 2A
receptors. Whole tissue PCR also identified adenosine A 3 receptors in the brain and A 3 …

Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus

N Rebola, RJ Rodrigues, LV Lopes, PJ Richardson… - Neuroscience, 2005 - Elsevier
Adenosine is a neuromodulator that controls neurotransmitter release through inhibitory A1
and facilitatory A2A receptors. Although both adenosine receptor-mediated inhibition and …

Adenosine A2B receptors

I Feoktistov, I Biaggioni - Pharmacological reviews, 1997 - ASPET
Adenosine is an endogenous nucleoside that modulates many physiological processes. Its
actions are mediated by interaction with specific cell membrane receptors. Four subtypes of …

Further characterization of the binding of the adenosine receptor agonist [3H] CGS 21680 to rat brain using autoradiography

B Johansson, BB Fredholm - Neuropharmacology, 1995 - Elsevier
2-[p-(2-carboxyethyl)-phenylethylamino]-5′-N-ethylcarboxamidoadenosine (CGS 21680) is
considered a selective ligand for adenosine A2A receptors, which are known to be enriched …

Adenosine receptors and the central nervous system

AM Sebastiao, JA Ribeiro - Adenosine receptors in health and disease, 2009 - Springer
The adenosine receptors (ARs) in the nervous system act as a kind of “go-between” to
regulate the release of neurotransmitters (this includes all known neurotransmitters) and the …

Adenosine receptor subtypes: binding studies

RF Bruns, GH Lu, TA Pugsley - … of the 3rd International Symposium on …, 1987 - Springer
Adenosine receptors are divided into two main subtypes, designated A 1 and A 2. Although
the two subtypes are presently defined by structure-activity relationships, the original …

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

KA Jacobson, KS Park, JL Jiang, YC Kim, ME Olah… - …, 1997 - Elsevier
The effects of putative A3 adenosine receptor antagonists of three diverse chemical classes
(the flavonoid MRS 1067, the 6-phenyl-1, 4-dihydropyridines MRS 1097 and MRS 1191 …

Blocking striatal adenosine A2A receptors: a new strategy for basal ganglia disorders

CE Muller, S Ferré - Recent Patents on CNS Drug Discovery …, 2007 - ingentaconnect.com
Adenosine A2A receptors are highly concentrated in the striatum, where they play an
important modulatory role of glutamatergic transmission to the GABAergic enkephalinergic …

[HTML][HTML] Glutamate residues in the second extracellular loop of the human A2a adenosine receptor are required for ligand recognition

J Kim, Q Jiang, M Glashofer, S Yehle… - Molecular …, 1996 - ncbi.nlm.nih.gov
The A 2a adenosine receptor, a member of the G protein-coupled receptor family, is
important in the regulation of dopaminergic pathways of the brain and in platelet and …