Until now, the efficiency of animal cloning by somatic cell nuclear transfer (SCNT) has
remained low. Efforts to improve cloning efficiency have demonstrated a positive role of …

Many different approaches have been developed to improve the efficiency of animal cloning
by somatic cell nuclear transfer (SCNT), one of which is to modify histone acetylation levels …

Although cloning by somatic cell nuclear transfer (SCNT) has been achieved in various
mammalian species, its efficiency has been very low (Han et al. 2003 Theriogenology 59, 33 …

Epigenetic aberrancies likely preclude correct and complete nuclear reprogramming after
somatic cell nucleus transfer (SCNT) and may underlie the observed reduced viability of …

Successful cloning by somatic cell nuclear transfer (SCNT) requires a reprogramming
process in which the epigenetic state of a differentiated donor nucleus must be converted …

The low viability of embryos reconstructed by somatic cell nuclear transfer (SCNT) is
believed to be associated with epigenetic modification errors, and reduction of those errors …

Epigenetic aberrancies likely preclude correct and complete nuclear reprogramming
following somatic cell nuclear transfer (SCNT), and may underlie the observed reduced …

The efficiency of somatic cell nuclear transfer (SCNT) is low in the rabbit. So far, there have
been few live births reported and most clones died within the first 3 weeks after birth. It has …

Abnormal epigenetic reprogramming, such as histone acetylation, might cause low
efficiency of interspecies somatic cell nuclear transfer (iSCNT). This study was conducted to …

We studied the effects of trichostatin A (TSA), a histone deacetylase inhibitor, on the
development of bovine somatic cell nuclear transfer (SCNT) embryos by investigating (1) the …