Marfan syndrome (MFS) is one of the most frequent connective tissue disorders, showing
striking pleiotropism and clinical variability. There is autosomal dominant inheritance with …

Marfan syndrome (MFS) is a connective tissue disorder with autosomal dominant
inheritance. Advances in medicine and surgery have increased the average lifespan of …

Abstract Background Patients with Marfan syndrome (MFS) are at risk for cardiovascular
disease. Marfan associated mutations in the FBN1 gene lead to increased transforming …

Marfan syndrome is a multi-system connective tissue disorder, with primary involvement of
the cardiovascular, ocular and skeletal systems. This autosomal heritable disease is mainly …

Objective: Mutations in the genes encoding fibrillin-1 (FBN1) and transforming growth factor
beta receptor type II (TGFBR2) are known causes of Marfan syndrome (MFS) and related …

Objective: Marfan syndrome (MFS) is caused by mutations in FBN1 (fibrillin-1), an
extracellular matrix (ECM) component, which is modified post-translationally by …

Marfan syndrome (MFS) is a rare inherited disorder of the connective tissue with an
autosomal dominant mode of inheritance which happens as a result of a mutation in the …

The Marfan syndrome (MFS) is an autosomal dominant heritable disorder of connective
tissue with highly variable clinical manifestations including aortic dilatation and dissection …

Marfan syndrome (MFS) is an autosomal dominant disorder of the connective tissue
characterized by early development of thoracic aortic aneurysms/dissections together with …

Marfan syndrome (MFS) is a connective tissue disease inherited in an autosomal dominant
fashion and associated with a decreased life expectancy. Skeletal features as well as a …