Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important
functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors …

Introduction• The somatostatin receptor as a GPCR• Anti‐tumour effects of somatostatin•
Post‐receptor signalling pathways‐Phosphotyrosine phosphatases and their action on …

Somatostatin (SST) is a small peptide that exerts inhibitory effects on a wide range of
neuroendocrine cells. Due to the fact that somatostatin regulates cell growth and hormone …

• Conclusions 2586 reconsidered, it is also understandable that not always will these two
components go hand in hand in every tumour treated. There are GH-secreting pituitary …

Somatostatin receptors are a pivotal target for treatment of pancreatic neuroendocrine
tumors (pNET), either with somatostatin analogues (SSA) or radiolabeled SSA. The highest …

Neuroendocrine neoplasms (NENs) show wide spectrum of clinical course—from benign
biological potential to recurrences and rapidly progressive disease. Somatostatin analogs …

© 2012 The Japan Society of Histochemistry and Molecule targeting therapy using
somatostatin (SS) analogues has become a widely accepted modality to treat …

Somatostatin analogs for the diagnosis and therapy of neuroendocrine tumors (NETs) have
been used in clinical applications for more than two decades. Five somatostatin receptor …

Well-differentiated neuroendocrine tumors (NT) expresses somatostatin receptors (sstr). A
composition of sstr subtype determines biological behavior. We therefore evaluated their …

Somatostatin (SST), a growth hormone inhibitory peptide, is expressed in endocrine and
non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release …