'Hunger is the best spice'is an old and wise saying that acknowledges the fact that almost
any food tastes better when we are hungry. The neurobiological underpinnings of this lore …

Obesity has become one of the leading causes of illness and mortality in the developed
world. Preclinical and clinical data provide compelling evidence for ghrelin as a relevant …

The endogenous ligand for the growth hormone secretagogue receptor, ghrelin, is a 28–
amino-acid peptide acylated with an octanoyl group at the serine in position 3. Most of the …

Discovered as a peptide involved in releasing growth hormone, ghrelin was initially
characterized as the “hunger hormone.” However, emerging research indicates that ghrelin …

In addition to ghrelin's effects on appetite and adiposity, ghrelin signalling also plays crucial
roles in glucose and energy homeostasis, cardioprotection, muscle atrophy and bone …

Ghrelin and the growth hormone secretagogue receptor 1a (GHS-R1a) are important targets
for disorders related to energy balance and metabolic regulation. Pharmacological control of …

The recently discovered hormone, ghrelin, has been recognized as an important regulator of
GH secretion and energy homeostasis. Orexigenic and adipogenic ghrelin is produced by …

Ghrelin, a 28-amino acid peptide hormone expressed in X/A-like endocrine cells of the
stomach, is the only known peripherally produced and centrally acting peptide that …

Ghrelin is a recently identified endogenous ligand for the growth hormone secretagogue
receptor. It is synthesized predominantly in the stomach and found in the circulation of …

Ghrelin, a hormone that is produced mainly by the stomach, was identified originally as the
endogenous ligand of the growth hormone secretagogue (GHS) receptor. Ghrelin might also …