Tumors, wounds, and chronic inflammatory disorders generate a new vascular supply by a
process known as pathological angiogenesis. Whereas formation of the normal blood …

Angiogenesis, the formation of new networks of blood vessels, has essential roles in
embryonic development, organ homeostasis and disease progression. Several signalling …

Angiogenesis has critical roles in normal vascular development and in important
pathologies including cancer, wound healing and inflammation. This brief article will review …

VEGF-B, a homolog of VEGF discovered a long time ago, has not been considered an
important target in antiangiogenic therapy. Instead, it has received little attention from the …

Angiogenesis, or formation of new blood vessels from pre-existing ones, is essential for
normal development and wound healing/reproductive functions in adults. Abnormal …

Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various
ischemic and inflammatory diseases. A rich variety of pro-and antiangiogenic molecules …

In this review we summarize the current understanding of signal transduction downstream of
vascular endothelial growth factor A (VEGFA) and its receptor VEGFR 2, and the relationship …

Growth of new blood vessels (angiogenesis), required for all tumor growth, is stimulated by
the expression of vascular endothelial growth factor (VEGF). VEGF is up-regulated in all …

Judah Folkman recognized that new blood vessel formation is important for tumor growth
and proposed antiangiogenesis as a novel approach to cancer therapy. Discovery of …

The vascular endothelial growth factor (VEGF) family of proteins regulates blood flow,
growth, and function in both normal physiology and disease processes. VEGF-A is …