Interleukin-6 is a cytokine not only involved in inflammation and infection responses but also
in the regulation of metabolic, regenerative, and neural processes. In classic signaling …

Abstract Interleukin (IL)-15, a member of the immunoregulatory cytokines family, is a
pluripotent molecule with therapeutic potential. It is predominantly expressed by the myeloid …

Interleukin-6 (IL-6) was identified based on extensive research conducted simultaneously on
a variety of topics ranging from hepatocyte production of acute-phase proteins to …

Cytokines receptors exist in membrane bound and soluble form. A soluble form of the
human IL-6R is generated by limited proteolysis and alternative splicing. The complex of IL …

IL-6 signaling plays a prominent role in tumorigenesis and metastasis. In this review we
discuss the recent evidence describing the tumor intrinsic and extrinsic functions of this …

Abstract The interleukin (IL)-1 family of cytokines comprises 11 members, including 7 pro-
inflammatory agonists (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and 4 defined or …

Interleukin‐10 (IL‐10) is unique among cytokines, as it is considered both as a potent
immunostimulatory and immunosuppressive factor. This complex biology has been …

Simple Summary Interleukin-1 cytokines are key proinflammatory cytokines which have
been implicated with differing pro-and antitumorigenic properties. Recent years have …

The balance of proinflammatory cytokines interleukin (IL)-12 and IL-23 plays a key role in
shaping the development of antitumor or protumor immunity. In this review, we discuss the …

Interleukin-6 (IL-6) is a pleiotropic cytokine involved in the regulation of the cross talk
between haematopoietic/immune cells and stromal cells, including the onset and resolution …