Preserving and perfusing the allograft pancreas: past, present, and future

S Dholakia, E Royston, EJ Sharples, V Sankaran… - Transplantation …, 2018 - Elsevier
The concept of organ preservation by perfusion dates back to the mid-19th century.
Innovations since then have included temperature regulation, perfusion fluid composition …

Pancreas preservation for pancreas and islet transplantation: a minireview

JP Squifflet, H LeDinh, A de Roover… - Transplantation …, 2011 - Elsevier
Pancreas preservation by cold storage using University of Wisconsin solution was the
mainstay method used for pancreas transplantation during the past 2 decades. Other …

Normothermic ex vivo pancreas perfusion for the preservation of pancreas allografts before transplantation

C Parmentier, S Ray, L Mazilescu, M Kawamura… - JoVE (Journal of …, 2022 - jove.com
Pancreas transplantation (PTx) is a curative treatment for people who live with the burden of
a diagnosis of diabetes mellitus (DM). However, due to organ shortages and increasing …

Ischemia-reperfusion injuries assessment during pancreas preservation

T Prudhomme, JF Mulvey, LAJ Young… - International Journal of …, 2021 - mdpi.com
Maintaining organ viability between donation and transplantation is of critical importance for
optimal graft function and survival. To date in pancreas transplantation, static cold storage …

[HTML][HTML] A systematic review and meta-analysis of cold in situ perfusion and preservation for pancreas transplantation

AM Hameed, G Wong, JM Laurence, VWT Lam… - Hpb, 2017 - Elsevier
Background This study aimed to identify the most effective solution for in situ
perfusion/preservation of the pancreas in donation after brain death donors, in addition to …

Machine perfusion and the pancreas: will it increase the donor pool?

K Hamaoui, V Papalois - Current Diabetes Reports, 2019 - Springer
Abstract Purpose of Review Pancreas transplantation enables complete patient
independence from exogenous insulin administration and increases both patient survival …

Pancreas preservation for pancreas and islet transplantation

Y Iwanaga, DER Sutherland, JV Harmon… - Current opinion in …, 2008 - journals.lww.com
Cold storage may be adequate for preservation before pancreas transplants, but insufficient
when pancreases are processed for islets or when expanded donors are used …

Extracorporeal machine perfusion of the pancreas: technical aspects and its clinical implications–a systematic review of experimental models

KG Kuan, MN Wee, WY Chung, R Kumar… - Transplantation …, 2016 - Elsevier
Pancreas or pancreatic islet transplantation is an important treatment option for insulin-
dependent diabetes and its complications. However, as the pancreas is particularly …

Preservation of canine segmental pancreatic autografts: cold storage versus pulsatile machine perfusion

G Florack, DER Sutherland, J Heil, JP Squifflet… - Journal of Surgical …, 1983 - Elsevier
The reliability of cold storage and pulsatile machine perfusion for preservation of open-duct
segmental pancreatic grafts for 24, 48, and 72 hours was determined in a canine autograft …

Ex situ perfusion of pancreas for whole-organ transplantation: is it safe and feasible? A systematic review

T Prudhomme, D Kervella… - Journal of diabetes …, 2020 - journals.sagepub.com
Introduction: Pancreas transplantation is currently one of the best treatments proposed in
highly selected patients with unstable and brittle type 1 diabetes. The objective of pancreas …