Cellular entry of nanoparticles via serum sensitive clathrin-mediated endocytosis, and plasma membrane permeabilization
PJ Smith, M Giroud, HL Wiggins, F Gower… - International journal …, 2012 - Taylor & Francis
Increasing production and application of nanomaterials raises significant questions
regarding the potential for cellular entry and toxicity of nanoparticles. It was observed that …
regarding the potential for cellular entry and toxicity of nanoparticles. It was observed that …
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
E Fröhlich - International journal of nanomedicine, 2012 - Taylor & Francis
Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …
Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier
Unraveling the mechanisms of nanoparticle transport across the intestinal barrier is
essential for designing more efficient nanoparticles for oral administration. The …
essential for designing more efficient nanoparticles for oral administration. The …
Translational considerations in nanomedicine: the oncology perspective
Nanoparticles can provide effective control of the release rate and tissue distribution of their
drug payload, leading to major pharmacokinetic and pharmacodynamic changes vis-à-vis …
drug payload, leading to major pharmacokinetic and pharmacodynamic changes vis-à-vis …
Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake
Delivery and toxicity are critical issues facing nanomedicine research. Currently, there is
limited understanding and connection between the physicochemical properties of a …
limited understanding and connection between the physicochemical properties of a …
[HTML][HTML] Introduction to nanomedicine
D Astruc - Molecules, 2015 - mdpi.com
Although mentions of nanoparticles in relation to biomedicine appeared in the late 1970s
and are now the subject of over 10,000 publications per year, the term “Nanomedicine” only …
and are now the subject of over 10,000 publications per year, the term “Nanomedicine” only …
Theranostic nanoparticles engineered for clinic and pharmaceutics
Nanomedicine is the manipulation of human biological systems at the molecular level using
nanoscale or nanostructured materials. Because nanoscale materials interact effectively …
nanoscale or nanostructured materials. Because nanoscale materials interact effectively …
Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications
The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …
nanotechnology offers enormous potential for improving cancer treatment strategies. The …
Experimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: toward models of uptake kinetics
Central to understanding how nanoscale objects interact with living matter is the need for
reproducible and verifiable data that can be interpreted with confidence. Likely this will be …
reproducible and verifiable data that can be interpreted with confidence. Likely this will be …
[HTML][HTML] Effects of transport inhibitors on the cellular uptake of carboxylated polystyrene nanoparticles in different cell lines
Nanotechnology is expected to play a vital role in the rapidly developing field of
nanomedicine, creating innovative solutions and therapies for currently untreatable …
nanomedicine, creating innovative solutions and therapies for currently untreatable …