Homocysteine in neurology: from endothelium to neurodegeneration

R Moretti, M Dal Ben, S Gazzin… - Current Nutrition & Food …, 2017 - ingentaconnect.com
Vitamin B12 and folate are supplied via two major pathways, the conversion of
homocysteine to methionine and the conversion of methyl malonyl coenzyme A to succinyl …

[HTML][HTML] Homocysteine in neurology: a possible contributing factor to small vessel disease

R Moretti, M Giuffre, P Caruso, S Gazzin… - International Journal of …, 2021 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid generated during methionine
metabolism, accumulation of which may be caused by genetic defects or the deficit of …

Homocysteine in health and disease

SJ Moat, IFW McDowell - 2002 - academic.oup.com
Homocysteine is a sulphur-containing amino acid that was first discovered in 1932 and was
identified as a product of the essential amino acid, methionine. Its clinical significance …

Role of homocysteine in age-related vascular and non-vascular diseases

L Parnetti, T Bottiglieri, D Lowenthal - Aging Clinical and Experimental …, 1997 - Springer
Homocysteine (Hcy) may represent a metabolic link in the pathogenesis of atherosclerotic
vascular diseases and old-age dementias. Hyperhomocysteinemia is an independent risk …

[HTML][HTML] The controversial role of homocysteine in neurology: from labs to clinical practice

R Moretti, P Caruso - International journal of molecular sciences, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …

Hyperhomocysteinemia in neurologic diseases

A Siniscalchi - Recenti Progressi in Medicina, 2004 - europepmc.org
Homocysteine is a thyol amino acid resulting from a methylation of methionine, an essential
amino acid derived from dietary proteins. Homocysteine is metabolized through two …

[HTML][HTML] Involvements of hyperhomocysteinemia in neurological disorders

M Cordaro, R Siracusa, R Fusco, S Cuzzocrea… - Metabolites, 2021 - mdpi.com
Homocysteine (HCY), a physiological amino acid formed when proteins break down, leads
to a pathological condition called hyperhomocysteinemia (HHCY), when it is over a definite …

Homocysteine, vitamin determinants and neurological diseases.

R Ientile, M Curro, N Ferlazzo, S Condello… - Frontiers in …, 2010 - europepmc.org
This review focuses on the putative role of hyper-homocysteinemia in the pathogenesis of
different diseases affecting the nervous system, including stroke, Alzheimer's disease …

Homocysteine and cerebral ischemia: pathogenic and therapeutical implications

A Pezzini, E Del Zotto… - Current medicinal …, 2007 - ingentaconnect.com
Homocysteine is a thiol aminoacid synthesized during the metabolism of methionine.
Increased plasma levels of homocysteine can be the result of mutations in the enzymes …

The methionine-homocysteine cycle and its effects on cognitive diseases.(Homocysteine & Cognitive)

AL Miller - Alternative Medicine Review, 2003 - go.gale.com
Homocysteine, a sulfur-containing amino acid, is a metabolite of the essential amino acid
methionine, and exists at a critical biochemical intersection in the methionine cycle …