The aim of the present study was to evaluate the efficacy of paclitaxel combined with
curcumin (CUR) against drug resistance in ovarian cancer cells. PLGA-phospholipid-PEG …

Purpose The aim of this study was to test the ability of paclitaxel-loaded poly
(butylcyanoacrylate)(PBCA) nanoparticles to overcome multidrug resistance (MDR) in …

Objectives: Ovarian cancer has the highest mortality of all the gynecologic cancers. The
antitumor agent paclitaxel has been proved to be efficient in the treatment of ovarian cancer …

Background Ovarian cancer is the most leading cause of death and the third most common
gynecologic malignancy in women. Traditional chemotherapy has inevitable drawbacks of …

Paclitaxel is a microtubule inhibitor causing mitotic arrest and is widely used in cancer
chemotherapy. However, its poor water solubility restricts its direct clinical applications. In …

Paclitaxel (PTX) is frequently suffered from multidrug resistance (MDR), resulting in lower
chemotherapeutic efficacy and even chemotherapy failure. To combine the P-glycolprotein …

To find out potent paclitaxel (PTX) formulations for cancer chemotherapy, we formulated PTX
in O/W emulsion and liposome selected as candidates of nanocarriers for PTX. Surface …

The aim of this study was to evaluate the effect of curcumin (CUR) in oral bioavailability and
therapeutic efficacy of paclitaxel (PTX) administered in nanoemulsion to SKOV3 tumor …

Purpose The aim of this work was to prepare paclitaxel-loaded PLGA nanoparticles and
determine cytotoxicity of released paclitaxel for two hypoxic human tumor cell lines: breast …

Paclitaxel (PTX) is efficacious in treating various solid tumors. However, the severe adverse
effects of its present formulation (Cremophor EL and ethanol) and the development of drug …