The objective of the work was to develop a multifunctional nanomedicine based on a folate-
conjugated lipid nanoparticles loaded with paclitaxel and curcumin. The novel system …

The purpose of this work was to compare the in vitro and in vivo characteristics of LDV-
targeted lipid-based micelles, liposomes and solid lipid nanoparticles (SLN) to provide …

Cancer chemotherapeutic drug containing PEGylated lipidic nanocapsules (D-LNCs) were
formulated by the controlled addition of organic phase (combined solution of paclitaxel and …

Cationic paclitaxel nanoparticles were developed and the possible delivery mechanism was
explored by cellular uptake studies. In vitro cytotoxicity of paclitaxel-loaded nanoparticles …

Purpose The present studies evaluated the ability of paclitaxel (PTX) nanosuspension
coated with TPGS to reverse drug-resistance of P-glycoprotein (P-gp)-overexpressing H460 …

Background: Combination chemotherapy of chemo-drugs and natural herbal drugs has
been shown to be more advantageous than individual treatment with respect to enhancing …

Background PTX is one of the most widely used drug in oncology due to its high efficacy
against solid tumors and several hematological cancers. PTX is administered in a …

Ovarian cancer (OvCa) is currently the fifth most lethal malignancy affecting women health
owing to the lack of early diagnosis and treatment choices available before the disease has …

Taxanes, including paclitaxel, are anti-cancer drugs approved for the treatment of prostate
cancer but which have limited clinical application due to their hydrophobicity, their low …

In order to investigate the effect of chitosan/pshRNA plasmid nanoparticles targeting MDR1
genes on the resistance of A2780/TS cells to paclitaxel, chitosan/pshRNA plasmid …