Prediction and verification of potential lead analgesic and antiarrhythmic components in Corydalis yanhusuo WT Wang based on voltage-gated sodium channel …

J Sun, X Liu, S Zhao, S Zhang, L Yang, J Zhang… - International Journal of …, 2022 - Elsevier
Corydalis yanhusuo WT Wang, a traditional Chinese herbal medicine, has been used as an
analgesic for thousands of years and it also promotes blood circulation. In this study, 33 …

An integrated anti-arrhythmic target network of a Chinese medicine compound, Wenxin Keli, revealed by combined machine learning and molecular pathway analysis

T Wang, M Lu, Q Du, X Yao, P Zhang, X Chen… - Molecular …, 2017 - pubs.rsc.org
Wenxin Keli (WK), a Chinese patent medicine, is known to be effective against cardiac
arrhythmias and heart failure. Although a number of electrophysiological findings regarding …

An exploration in the potential substance basis and mechanism of chuanxiong rhizoma and Angelicae Dahuricae Radix on analgesia based on network …

TT Zhao, RR Lan, SD Liang… - World Journal of …, 2021 - journals.lww.com
Objective: The objective was to study the potential substance basis and action mechanism of
Chuanxiong Rhizoma (CX) and Angelicae Dahuricae Radix (AD) on analgesia through …

A network pharmacology study on analgesic mechanism of Yuanhu-Baizhi herb pair

B Mi, Q Li, T Li, J Marshall, J Sai - BMC Complementary Medicine and …, 2020 - Springer
Background Millions of people are suffering from chronic pain conditions, such as
headache, arthritis, cancer. Apart from western medicines, traditional Chinese medicines are …

Potential pharmacological mechanisms of tanshinone IIA in the treatment of human neuroblastoma based on network pharmacological and molecular docking …

N Tang, Y Wang, J Miao, Y Zhao, Y Cao… - Frontiers in …, 2024 - frontiersin.org
Tanshinone IIA (Tan-IIA) is the main bioactive component of Chinese herbal medicine salvia
miltiorrhiza (Danshen). Sodium sulfonate of Tan-IIA is widely used in the treatment of …

Predicting the mechanism of the analgesic property of yanhusuo based on network pharmacology

WP Xiao, YF Yang, HZ Wu… - Natural Product …, 2019 - journals.sagepub.com
Yanhusuo (Corydalis Rhizoma) extracts are widely used for the treatment of pain and
inflammation. The effects of Yanhusuo in pain assays were assessed in a few studies …

Identifying potential quality markers of Xin-Su-Ning capsules acting on arrhythmia by integrating UHPLC-LTQ-Orbitrap, ADME prediction and network target analysis

R Guo, X Zhang, J Su, H Xu, Y Zhang, F Zhang, D Li… - Phytomedicine, 2018 - Elsevier
Background Quality marker (Q-markers) has been proposed as a novel concept for quality
evaluation and standard elaboration of traditional Chinese medicine (TCM). Xin-Su-Ning …

Network toxicological analysis and mechanism prediction of cardiotoxicity of alkaloids in Aconiti Radix

F Qun, YAO Jingchun, LI Xin, J Fanbo, Z Na… - Chinese Journal of …, 2022 - zgywjj.com
Objective To explore and predict cardiotoxic targets and mechanism of alkaloids in Aconiti
Radix with network toxicology and molecular docking methods, and provide data for the …

Network pharmacology‐based analysis of the underlying mechanism of Huajiao for pain relief

M Wu, HL Du, X Zhou, W Peng, L Liu… - Evidence‐Based …, 2021 - Wiley Online Library
Objective. Pain is a common symptom among patients, and pain management is an
important clinical practice topic. The mechanism of Huajiao (HJ; Zanthoxylum bungeanum …

Network pharmacology-based strategy for predicting active ingredients and potential targets of Yangxinshi tablet for treating heart failure

L Chen, Y Cao, H Zhang, D Lv, Y Zhao, Y Liu… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Yangxinshi tablet (YXST) is an effective treatment for heart
failure and myocardial infarction; it consists of 13 herbal medicines formulated according to …