[HTML][HTML] The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR

A Chabowski, SLM Coort, J Calles-Escandon… - FEBS letters, 2005 - Elsevier
Cellular fatty acid uptake is facilitated by a number of fatty acid transporters, FAT/CD36,
FABPpm and FATP1. It had been presumed that FABPpm, was confined to the plasma …

[HTML][HTML] Hypoxia-induced fatty acid transporter translocation increases fatty acid transport and contributes to lipid accumulation in the heart

A Chabowski, J Górski, J Calles-Escandon, NN Tandon… - FEBS letters, 2006 - Elsevier
Protein-mediated LCFA transport across plasma membranes is highly regulated by the fatty
acid transporters FAT/CD36 and FABPpm. Physiologic stimuli (insulin stimulation, AMP …

Characterization of a heart-specific fatty acid transport protein

RE Gimeno, AM Ortegon, S Patel, S Punreddy… - Journal of Biological …, 2003 - ASBMB
Fatty acids are a major source of energy for cardiac myocytes. Changes in fatty acid
metabolism have been implicated as causal in diabetes and cardiac disease. The …

Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane

A Chabowski, J Górski, JJFP Luiken, JFC Glatz… - … and essential fatty acids, 2007 - Elsevier
There is substantial molecular, biochemical and physiologic evidence that long-chain fatty
acid transport involves a protein-mediated process. A number of fatty acid transport proteins …

Regulation of fatty acid transport and membrane transporters in health and disease

A Bonen, JJFR Luiken, JFC Glatz - Cellular Lipid Binding Proteins, 2002 - Springer
Long chain fatty acid uptake across the plasma membrane occurs, in part, via a protein-
mediated process involving a number of fatty acid binding proteins known as fatty acid …

Cellular fatty acid uptake is acutely regulated by membrane-associated fatty acid-binding proteins

J Luiken, A Bonen, JFC Glatz - Prostaglandins, leukotrienes and essential …, 2002 - Elsevier
Cellular long-chain fatty acid uptake is believed to occur largely by protein-mediated
transmembrane transport of fatty acids, and also by passive diffusional uptake. It is …

Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters

JJFP Luiken, SLM Coort, DPY Koonen… - Pfluegers Archiv, 2004 - Springer
Cardiac uptake of long-chain fatty acids (FA) is mediated predominantly by two membrane-
associated proteins, the 43-kDa plasma membrane fatty acid-binding protein (FABPpm) and …

Protein-mediated fatty acid uptake in the heart

A Chabowski, J Górski, JFC Glatz… - Current cardiology …, 2008 - ingentaconnect.com
Long chain fatty acids (LCFAs) provide 70-80% of the energy for cardiac contractile activity.
LCFAs are also essential for many other cellular functions, such as transcriptional regulation …

Critical steps in cellular fatty acid uptake and utilization

GJ van der Vusse, M van Bilsen, JFC Glatz… - Cellular Lipid Binding …, 2002 - Springer
Despite decades of extensive research, the transport routes, mechanisms of uptake and
points of flux control of long-chain fatty acids (FA) in mammalian organs are still incompletely …

Plasmalemmal fatty acid transport is regulated in heart and skeletal muscle by contraction, insulin and leptin, and in obesity and diabetes

A Bonen, CR Benton, SE Campbell… - Acta physiologica …, 2003 - Wiley Online Library
It has been assumed that the uptake of long chain fatty acids (LCFAs) into skeletal muscle
and the heart muscle, as well as other tissues, occurred via passive diffusion. In recent years …