A novel method of delivering cancer chemotherapeutic drugs to the brain in concentrations
higher than those achievable by standard routes of administration has been developed. The …

Implants providing controlled, local release of active substances are of interest in different
medical applications. Therefore, the focus of the present article is the development of …

(1) Background: The current limitations of glioblastoma (GBM) chemotherapy were
addressed by developing a molecularly imprinted polymer (MIP)-based drug reservoir …

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumour in
adults with a very poor prognosis. This paper describes the development of disulfiram (DSF) …

Glioma is the most invasive form of brain tumor, and usually causes death within months
after diagnosis. Delivering a high concentration of drug to the brain is difficult due to the …

Glioblastoma (GBM) is a primary brain tumor that carries a dismal prognosis, which is
primarily attributed to tumor recurrence after surgery and resistance to chemotherapy. Since …

Glioblastoma is characterized by diffuse infiltration into surrounding healthy brain tissues,
which makes it challenging to treat. Complete surgical resection is often impossible, and …

Glioblastoma multiforme (GBM) remains a major cause of mortality because treatments are
precluded by to the limited transport and penetration of chemotherapeutics across the blood …

Treating malignant brain tumors represents one of the most formidable challenges in
oncology. Contemporary treatment of brain tumors has been hampered by limited drug …

Brain tumor is one of the most challenging diseases to treat. The major obstacle in the
specific drug delivery to brain is blood–brain barrier (BBB). Mostly available anti-cancer …