Proteomics of human neurodegenerative diseases
The technology, experimental approaches, and bioinformatics that support proteomic
research are evolving rapidly. The application of these new capabilities to the study of …
research are evolving rapidly. The application of these new capabilities to the study of …
Clinical proteomics in neurodegenerative diseases
Investigation of the human specimens is an essential element for understanding the
pathogenesis of neurodegenerative disorders, such as Alzheimer's disease, Parkinson's …
pathogenesis of neurodegenerative disorders, such as Alzheimer's disease, Parkinson's …
Biomarker discovery in neurodegenerative diseases: a proteomic approach
Biomarkers for neurodegenerative disorders are essential to facilitate disease diagnosis,
ideally at early stages, monitor disease progression, and assess response to existing and …
ideally at early stages, monitor disease progression, and assess response to existing and …
Clinical proteomics in neurodegenerative disorders
H Zetterberg, U Rüetschi, E Portelius… - Acta Neurologica …, 2008 - Wiley Online Library
Neurodegenerative disorders are characterized by neuronal impairment that eventually
leads to neuronal death. In spite of the brain's known capacity for regeneration, lost neurons …
leads to neuronal death. In spite of the brain's known capacity for regeneration, lost neurons …
Proteomics of neurodegenerative diseases: analysis of human post‐mortem brain
KW Li, AB Ganz, AB Smit - Journal of neurochemistry, 2019 - Wiley Online Library
Dementias are prevalent brain disorders in the aged population. Dementias pose major
socio‐medical burden, but currently there is no cure available. Novel proteomics …
socio‐medical burden, but currently there is no cure available. Novel proteomics …
New insight into neurodegeneration: the role of proteomics
Recent advances within the field of proteomics, including both upstream and downstream
protocols, have fuelled a transition from simple protein identification to functional analysis. A …
protocols, have fuelled a transition from simple protein identification to functional analysis. A …
Proteomics of human cerebrospinal fluid: discovery and verification of biomarker candidates in neurodegenerative diseases using quantitative proteomics
There is an urgent need for novel biomarkers that can be used to improve the diagnosis,
predict the disease progression, improve our understanding of the pathology or serve as …
predict the disease progression, improve our understanding of the pathology or serve as …
The potential of proteomics in understanding neurodegeneration
Neurodegenerative diseases are a major health concern worldwide. Diseases such as
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …
The challenge to search for new nervous system disease biomarker candidates: the opportunity to use the proteogenomics approach
TGM Nery, EM Silva, R Tavares, F Passetti - Journal of Molecular …, 2019 - Springer
Alzheimer's disease, Parkinson's disease, prion diseases, schizophrenia, and multiple
sclerosis are the most common nervous system diseases, affecting millions of people …
sclerosis are the most common nervous system diseases, affecting millions of people …
Proteomic biomarker discovery in cerebrospinal fluid for neurodegenerative diseases
J Zhang, DR Goodlett… - Journal of Alzheimer's …, 2005 - content.iospress.com
The clinical diagnosis of major neurodegenerative disorders, eg Alzheimer's disease,
Parkinson's disease, and dementia with Lewy body, remains unsatisfactory based on current …
Parkinson's disease, and dementia with Lewy body, remains unsatisfactory based on current …
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