Although standard therapy for AML has been relatively constant over the past 2 decades,
this may be changing with enhanced technologies allowing for the classification of acute …

Acute myeloid leukemia (AML) is a biologically complex and molecularly and clinically
heterogeneous disease, and its incidence is increasing as the population ages …

The pathogenesis of acute myeloid leukaemias (AML) frequently requires at least 3
mutations in different cellular pathways. In many cases, mutations in proliferation/survival …

Abstract Purpose of Review The field of acute myeloid leukemia (AML) has been
revolutionized in recent years by the advent of high-throughput techniques, such as next …

Acute myeloid leukemia (AML) is the most frequently diagnosed acute leukemia, and its
incidence increases with age. Although the etiology of AML remains unknown, exposure to …

Acute myeloid leukemia (AML) represents a malignant accumulation of immature myeloid
cells in the marrow, presenting with impaired hematopoiesis and its attendant complications …

Research into the underlying pathogenic mechanisms of acute myeloid leukemia (AML) has
led to remarkable advances in our understanding of the disease. Mutations now allow us to …

Acute myeloid leukemia (AML) is a biologically complex and molecularly and clinically
heterogeneous disease, and its incidence increases with age. Cytogenetics and mutation …

Acute myeloid leukemia (AML) is a disease with marked heterogeneity in both response to
therapy and survival. Cytogenetics, age, and performance status have long determined …

For the first time in AML, personalized therapy has become possible through improved
understanding of the molecular architecture and survival pathways of an individual's …