We measured the response of normal brain and the human U87 glioma implanted in the
brain of rats (n= 65) to photodynamic therapy (PDT) using Photofrin as the sensitizer. Normal …

The extent of the apoptotic response of normal rat brain tissue to Photofrin-mediated
photodynamic therapy was determined following sub-necrotic light exposures. Wistar rats …

High concentrations of cellular glutathione (GSH) within tumour cells may reduce the ability
of photodynamic therapy (PDT) to selectively destroy tumour, consequently, a means of …

The use of PHOTOFRIN™ for photodynamic therapy of human gliomas has been studied by
iv administration and laser photosensitization. Defining the uptake of PHOTOFRIN™ in the …

The widespread acceptance of photodynamic therapy (PDT), a potential adjuvant brain
tumor therapy under clinical evaluation since 1980, has been partially restrained by its …

In this study we investigated the influence of Photofrin-based photodynamic therapy (PDT)
on the migration of two human glioma cell lines in vitro. U87 and U25ln tumour cells were …

Normal brain tissue response to photodynamic therapy (PDT) must be quantified in order to
implement PDT as a treatment of brain neoplasm. We therefore calculated the threshold for …

PDT included necrosis in brain tissue and an intracranial tumor has been quantified for
various photosensitizers, and it has been shown to be dependent on the sub-cellular …

The effect of Photofrin encapsulated in a liposome delivery vehicle for photodynamic therapy
(PDT) of the 9L gliosarcoma and normal rat brain was tested. We hypothesized that the …

The objective of this study is to measure the chronic responses of 9L glioma and normal
brain to photodynamic therapy (PDT). Tumor size, proliferation activity of glioma cells, and …