Standard two/three dimensional (2D/3D)-cell culture platforms have facilitated the
understanding of the communications between various cell types and their …

The intestinal epithelium has one of the highest turnover rates in the human body, which is
supported by intestinal stem cells. Culture models of intestinal physiology have been …

The intestine is a visceral organ that integrates absorption, metabolism, and immunity, which
is vulnerable to external stimulus. Researchers in the fields such as food science …

Implementations of suitable in vitro cell culture systems of the human intestine have been
essential tools in the study of the interaction among organs, commensal microbiota …

Over the past years, several preclinical in vitro and ex vivo models have been developed
that helped to understand some of the critical aspects of intestinal functions in health and …

Over the past decade, microfluidic intestine-on-a-chip models have been emerging as a
novel platform to study intestinal function in health and disease. These microphysiological …

The intestinal epithelium, the fastest renewing tissue in human, is a complex tissue hosting
multiple cell types with a dynamic and multiparametric microenvironment, making it …

Microfluidic organ-on-a-chip models of human intestine have been developed and used to
study intestinal physiology and pathophysiology. In this article, we review this field and …

Patients with short bowel syndrome lack sufficient functional intestine to sustain themselves
with enteral intake alone. Transplantable vascularized bioengineered intestine could restore …

Intestinal dysfunction is frequently driven by abnormalities of specific genes, microbiota, or
microenvironmental factors, which usually differ across individuals, as do intestinal …