Fluorescence time-resolved macroimaging

VI Shcheslavskiy, MV Shirmanova, VV Dudenkova… - Optics letters, 2018 - opg.optica.org
While laser scanning fluorescence lifetime imaging (FLIM) is a powerful approach for cell
biology, its small field of view (typically less than 1 mm) makes it impractical for the imaging …

Time-domain fluorescence lifetime imaging applied to biological tissue

D Elson, J Requejo-Isidro, I Munro, F Reavell… - Photochemical & …, 2004 - Springer
Fluorescence lifetime imaging (FLIM) is a functional imaging methodology that can provide
information, not only concerning the localisation of specific fluorophores, but also about the …

High-speed multispectral fluorescence lifetime imaging implementation for in vivo applications

S Shrestha, BE Applegate, J Park, X Xiao, P Pande… - Optics Letters, 2010 - opg.optica.org
Fluorescence lifetime imaging microscopy (FLIM) offers a noninvasive approach for
characterizing the biochemical composition of biological tissue. In recent years, there has …

Biomedical applications of fluorescence lifetime imaging

D Elson, S Webb, J Siegel, K Suhling… - Optics and photonics …, 2002 - opg.optica.org
Biomedical Applications of Fluorescence Lifetime Imaging Page 1 Dan Elson, Stephen
Webb, Jan Siegel, Klaus Suhling, Dan Davis, John Lever, David Phillips, Andrew Wallace …

Fast single-cell biochemistry: theory, open source microscopy and applications

AL Trinh, S Ber, A Howitt, PO Valls… - … and applications in …, 2019 - iopscience.iop.org
Fluorescence lifetime sensing enables researchers to probe the physicochemical
environment of a fluorophore providing a window through which we can observe the …

Fast fluorescence lifetime imaging techniques: A review on challenge and development

X Liu, D Lin, W Becker, J Niu, B Yu, L Liu… - Journal of Innovative …, 2019 - World Scientific
Fluorescence lifetime imaging microscopy (FLIM) is increasingly used in biomedicine,
material science, chemistry, and other related research fields, because of its advantages of …

Fluorescence lifetime imaging–techniques and applications

W Becker - Journal of microscopy, 2012 - Wiley Online Library
Fluorescence lifetime imaging (FLIM) uses the fact that the fluorescence lifetime of a
fluorophore depends on its molecular environment but not on its concentration. Molecular …

Fluorescence lifetime imaging microscopy for quantitative biological imaging

LC Chen, WR Lloyd III, CW Chang, D Sud… - Methods in cell biology, 2013 - Elsevier
Fluorescence lifetime imaging microscopy (FLIM) is a method for measuring fluorophore
lifetimes with microscopic spatial resolution, providing a useful tool for cell biologists to …

Fluorescence lifetime system for microscopy and multiwell plate imaging with a blue picosecond diode laser

DS Elson, J Siegel, SED Webb, S Lévêque-Fort… - Optics letters, 2002 - opg.optica.org
We report a wide-field fluorescence lifetime imaging (FLIM) system that uses a blue
picosecond pulsed diode laser as the excitation source. This represents a significant …

A novel fluorescence lifetime imaging system that optimizes photon efficiency

RA Colyer, C Lee, E Gratton - Microscopy research and …, 2008 - Wiley Online Library
Fluorescence lifetime imaging (FLIM) is a powerful microscopy technique for providing
contrast of biological and other systems by differences in molecular species or their …