There is increasing evidence showing that inflammation is associated with depression in
humans. Hesperidin, a natural bioflavonoid, has performed excellent effects on depression …

Objective Major depressive disorder (MDD) is a debilitating psychiatric disorder which is
common and endangers human physical and mental health. Studies have shown that …

Hesperidin, a kind of citrus bioflavonoid distributed in foods including grapefruits, oranges
and lemons, has many pharmacological activities. This study was aimed to evaluate the anti …

Background Depression is a common kind of mental illness, and it becomes the main health
burden in the world. Purpose The aim of this study was to investigate the antidepressant …

Previous studies have demonstrated that hesperidin, a flavanone glycoside from citrus fruits,
produces antidepressant-like effects in both mice and rats. However, whether these effects …

Background: Depression is a common and potentially life-threatening mental illness, and
currently, there is a lack of effective treatment. It has been reported that dehydrocorydaline …

Aims There is increasing evidence showing that mild traumatic brain injury (mTBI) is
associated with increased depression-related disorders in humans. Recent studies suggest …

Background Major depressive disorder is a serious psychiatric illness having serious
damaging effect on the quality of life of suffers. Quercetin is a plant flavonoid, mostly used as …

Abnormal activation of nucleotide-binding domain, leucine-rich repeat, pyrin domain
containing protein 3 (NLRP3) inflammasome could induce inflammation in the central …

α-Cyperone (Cy) is a major active compound of Cyperus rotundus that has various
pharmacological activities. But whether Cy possesses antidepressant effect is unknown. In …