The Agouti-related protein and its role in energy homeostasis

AM Stütz, CD Morrison, G Argyropoulos - Peptides, 2005 - Elsevier
The melanocortin system plays an important role in the regulation of energy homeostasis.
The Agouti-related protein (AGRP) is a natural antagonist of the action of alpha-melanocyte …

Expression of agouti-related protein (AgRP) in the hypothalamus and adrenal gland of the duck (Anas platyrhynchos)

N Mirabella, V Esposito, C Squillacioti… - Anatomy and …, 2004 - Springer
The presence and distribution of agouti-related protein (AgRP) immunoreactivity were
investigated in the hypothalamus and adrenal gland of the duck using …

Short‐days induce weight loss in Siberian hamsters despite overexpression of the agouti‐related peptide gene

PH Jethwa, A Warner, MJ Fowler… - Journal of …, 2010 - Wiley Online Library
Many vertebrates express profound annual cycles of body fattening, although it is not clear
whether these represent differential activity of the central pathways known to mediate …

Selective tissue uptake of agouti-related protein (82–131) and its modulation by fasting

W Pan, AJ Kastin, Y Yu, CM Cain, T Fairburn… - …, 2005 - academic.oup.com
The blood concentration of agouti-related protein (AgRP), a protein related to hyperphagia
and obesity, is increased in obese human and fasted lean subjects. Because there is no …

AgRP knockdown blocks long-term appetitive, but not consummatory, feeding behaviors in Siberian hamsters

MA Thomas, V Tran, V Ryu, B Xue, TJ Bartness - Physiology & behavior, 2018 - Elsevier
Arcuate hypothalamus-derived agouti-related protein (AgRP) and neuropeptide Y (NPY) are
critical for maintaining energy homeostasis. Fasting markedly upregulates AgRP/NPY …

Regulation of agouti-related protein messenger ribonucleic acid transcription and peptide secretion by acute and chronic inflammation

JM Scarlett, X Zhu, PJ Enriori, DD Bowe… - …, 2008 - academic.oup.com
Agouti-related protein (AgRP) is an orexigenic neuropeptide produced by neurons in the
hypothalamic arcuate nucleus (ARC) that is a key component of central neural circuits that …

Plasma agouti‐related protein level: a possible correlation with fasted and fed states in humans and rats

CP Shen, KK Wu, LP Shearman… - Journal of …, 2002 - Wiley Online Library
We measured plasma concentrations of agouti‐related protein (AGRP) in humans and rats
and determined whether these were affected by ingestion of a meal after fasting. In 17 …

Agouti-related protein increases food hoarding more than food intake in Siberian hamsters

DE Day, TJ Bartness - American Journal of Physiology …, 2004 - journals.physiology.org
Agouti-related protein (AgRP), an endogenous melanocortin 3/4 receptor antagonist,
appears to play an important role in the control of food intake and energy balance because …

Transcriptional Regulation of Agouti-Related Protein (Agrp) in Transgenic Mice

CB Kaelin, AW Xu, XY Lu, GS Barsh - Endocrinology, 2004 - academic.oup.com
Agouti-related protein (Agrp) encodes a hypothalamic neuropeptide that promotes positive
energy balance by stimulating food intake and reducing energy expenditure. Agrp …

The role of the Agouti-Related Protein in energy balance regulation

O Ilnytska, G Argyropoulos - Cellular and molecular life sciences, 2008 - Springer
The Agouti-Related Protein (AgRP) is a powerful orexigenic peptide that increases food
intake when ubiquitously overexpressed or when administered centrally. AgRP-deficiency …