Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice

S Qian, H Chen, D Weingarth… - … and cellular biology, 2002 - Am Soc Microbiol
Abstract Agouti-related protein (AgRP), a neuropeptide abundantly expressed in the arcuate
nucleus of the hypothalamus, potently stimulates feeding and body weight gain in rodents …

Agouti-related protein stimulates the hypothalamic-pituitary-adrenal (HPA) axis and enhances the HPA response to interleukin-1 in the primate

E Xiao, L Xia-Zhang, NR Vulliémoz, M Ferin… - …, 2003 - academic.oup.com
α-MSH antagonizes many of the immune and neuroendocrine effects induced by
inflammatory cytokines. Studies have shown that α-MSH attenuates the stimulatory effect of …

Effect of Agouti-related protein delivered to the dorsomedial nucleus of the hypothalamus on intake of a preferred versus a non-preferred diet

MM Wirth, SQ Giraudo - Brain research, 2001 - Elsevier
Agouti-related protein (Agrp), a high-affinity antagonist of the melanocortin-3/4 receptors,
increases feeding when administered centrally. Previous studies have shown that this …

Agouti‐related protein: appetite or reward?

PK Olszewski, K Wickwire, MM Wirth… - Annals of the New …, 2003 - Wiley Online Library
Agouti‐related protein (AgRP) is an orexigenic peptide that acts as an antagonist of the
melanocortin‐3 and‐4 receptors in the hypothalamus. Studies suggest that the melanocortin …

Glucose injection reduces neuropeptide Y and agouti-related protein expression in the arcuate nucleus: a possible physiological role in eating behavior

GQ Chang, O Karatayev, Z Davydova, K Wortley… - Molecular brain …, 2005 - Elsevier
Evidence suggests that neuropeptide Y (NPY) and agouti-related protein (AgRP) in the
arcuate nucleus (ARC) are modulated by glucoregulatory hormones and involved in …

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

H Makimura, TM Mizuno, JW Mastaitis, R Agami… - BMC neuroscience, 2002 - Springer
Background Several lines of evidence strongly suggest that agouti-related peptide (AGRP)
plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no …

Agouti-related protein in the hypothalamic paraventricular nucleus: effect on feeding

MM Wirth, SQ Giraudo - Peptides, 2000 - Elsevier
Agouti-related protein (Agrp) is an endogenous melanocortin-4 receptor antagonist
implicated in the regulation of food intake. Effects of Agrp on feeding under varying …

AgRP neuron-specific deletion of glucocorticoid receptor leads to increased energy expenditure and decreased body weight in female mice on a high-fat diet

M Shibata, R Banno, M Sugiyama, T Tominaga… - …, 2016 - academic.oup.com
Agouti-related protein (AgRP) expressed in the arcuate nucleus is a potent orexigenic
neuropeptide, which increases food intake and reduces energy expenditure resulting in …

Hypothalamic neuropeptide expression following chronic food restriction in sedentary and wheel-running rats

CE De Rijke, JJG Hillebrand… - Journal of …, 2005 - jme.bioscientifica.com
When rats are given access to a running-wheel in combination with food restriction, they will
become hyperactive and decrease their food intake, a paradoxical phenomenon known as …

Immunolesion of Norepinephrine and Epinephrine Afferents to Medial Hypothalamus Alters Basal and 2-Deoxy-d-Glucose-Induced Neuropeptide Y and Agouti Gene …

GS Fraley, S Ritter - Endocrinology, 2003 - academic.oup.com
Neuropeptide Y (NPY) and agouti gene-related protein (AGRP) are orexigenic peptides of
special importance for control of food intake. In situ hybridization studies have shown that …