Agouti-related protein (AgRP) is an endogenous antagonist at the melanocortin 3 and 4
receptor in the hypothalamus. Central administration of AgRP produces a robust increase in …

Agouti-related peptide (AgRP) neurons of the hypothalamus release a fast transmitter
(GABA) in addition to neuropeptides (neuropeptide Y [NPY] and Agouti-related peptide …

A novel RIA was used to examine the release of agouti-related protein-like immunoreactivity
(AGRP-LI) from perfused rat hypothalamic tissue slices and to characterize AGRP-LI in rat …

The central melanocortin system plays an important role in the regulation of energy
homeostasis both in rodents and humans, and melanocortin receptors appear to be the core …

Stress affects eating behaviour in rodents and humans, suggesting that the regulation of
energy balance and the stress response are coupled physiological processes …

The agouti-related protein (AgRP) is a powerful appetite modulator expressed in the
hypothalamus and the adrenal gland and regulated by leptin. Here we report the robust …

The regulation of neuroendocrine electrical activity and gene expression by glucose is
mediated through several distinct metabolic pathways. Many studies have implicated AMP …

Agouti-related protein (AGRP) has been implicated in the regulation of metabolic balance.
Overexpression of this peptide leads to obesity. Its activity is mediated via the melanocortin …

Several lines of evidence substantiate the important role of the central nervous system
melanocortin 3-and 4-receptor (MC3/4-R) system in the control of food intake and energy …

Energy homeostasis depends on the regulation of hypothalamic neurons by leptin, an
adipocyte hormone whose circulating levels communicate body energy stores. Leptin …