Neurons expressing neuropeptide Y mRNA in the infundibular hypothalamus of Japanese quail are activated by fasting and co-express agouti-related protein mRNA

T Boswell, Q Li, S Takeuchi - Molecular Brain Research, 2002 - Elsevier
The neural mechanisms involved in the compensatory hyperphagia exhibited by many
vertebrate species after a fast are not fully understood but, in mammals, appear to involve …

Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis

L Gong, F Yao, K Hockman, HH Heng, GJ Morton… - …, 2008 - academic.oup.com
Signal transducer and activator of transcription (Stat)-3 signals mediate many of the
metabolic effects of the fat cell-derived hormone, leptin. In mice, brain-specific depletion of …

Function of neuropeptide Y and agouti-related protein at weaning: relation to corticosterone, dietary carbohydrate and body weight

SF Leibowitz, K Sepiashvili, A Akabayashi… - Brain research, 2005 - Elsevier
Neuropeptide Y (NPY) and agouti-related protein (AgRP), potent stimulants of feeding, have
been linked in adult rats to both corticosterone (CORT) and dietary carbohydrate. To …

Arcuate nucleus destruction does not block food deprivation-induced increases in food foraging and hoarding

MJ Dailey, TJ Bartness - Brain research, 2010 - Elsevier
The mechanisms underlying the control of food intake are considerably better understood
than those underlying the appetitive ingestive behaviors of foraging and hoarding of food …

Agouti-related protein (83-132) aggregates and crosses the blood-brain barrier slowly

AJ Kastin, V Akerstrom… - Metabolism-Clinical and …, 2000 - metabolismjournal.com
Abstract Agouti-related protein (AgRP), expressed in both the periphery and the brain, can
result in obesity. Its active C-terminal fragment, AgRP (83-132), was recently reported to …

Biochemical, biophysical, and pharmacological characterization of bacterially expressed human agouti-related protein

RD Rosenfeld, L Zeni, AA Welcher, LO Narhi… - Biochemistry, 1998 - ACS Publications
The agouti-related protein gene (Agrp) is a novel gene implicated in the control of feeding
behavior. The hypothalamic expression of Agrp is regulated by leptin, and overexpression of …

AgRP neurons control compulsive exercise and survival in an activity-based anorexia model

MC Miletta, O Iyilikci, M Shanabrough… - Nature …, 2020 - nature.com
Hypothalamic agouti-related peptide (AgRP) and neuropeptide Y-expressing neurons have
a critical role in driving food intake, but also in modulating complex, non-feeding behaviours …

Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y/Agouti-related protein …

KA Takahashi, RD Cone - Endocrinology, 2005 - academic.oup.com
The neuropeptide Y (NPY)/Agouti-related protein (AgRP) neurons of the hypothalamic
arcuate nucleus are thought to promote feeding. Here, we demonstrate that feeding state in …

[HTML][HTML] Fasting induces remodeling of the orexigenic projections from the arcuate nucleus to the hypothalamic paraventricular nucleus, in a growth hormone …

A Cabral, G Fernandez, MJ Tolosa, ÁR Moggia… - Molecular …, 2020 - Elsevier
Objective Arcuate nucleus (ARC) neurons producing Agouti-related peptide (AgRP) and
neuropeptide Y (NPY; ARC AgRP/NPY neurons) are activated under energy-deficit states …

Chronic CNS administration of Agouti-related protein (Agrp) reduces energy expenditure

CJ Small, YL Liu, SA Stanley, IP Connoley… - International journal of …, 2003 - nature.com
OBJECTIVE: To investigate whether the Agouti-related protein (Agrp), the melanocortin
receptor antagonist, alters oxygen consumption, as a measure of energy expenditure …