Background Pregnancy malaria is caused by Plasmodium falciparum-infected erythrocytes
binding the placental receptor chondroitin sulfate A (CSA). This results in accumulation of …

Malaria is a major global health problem. Pregnant women are susceptible to infection
regardless of previously acquired immunity. Placental malaria is caused by parasites …

Malaria during pregnancy causes serious disease that is associated with sequestration in
the placenta of Plasmodium falciparum infected erythrocytes that adhere to several host …

In high‐transmission regions, protective clinical immunity to Plasmodium falciparum
develops during the early years of life, limiting serious complications of malaria in young …

Plasmodium falciparum parasites that bind to chondroitin sulphate A (CSA) express unique
variant surface antigens that are involved in the placental sequestration that precipitates …

Background VAR2CSA is a large polymorphic Plasmodium falciparum protein expressed on
infected erythrocytes (IE) that allows their binding in the placenta, thus precipitating …

Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and
infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental …

Placental malaria is a serious problem in sub-Saharan Africa. Young women are particular
susceptible to contracting this form of malaria during their first or second pregnancy despite …

VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of
infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous …

Malaria during pregnancy is a major health problem for African women. The disease is
caused by Plasmodium falciparum malaria parasites, which accumulate in the placenta by …