[HTML][HTML] Ultrafast two-photon imaging of a high-gain voltage indicator in awake behaving mice

V Villette, M Chavarha, IK Dimov, J Bradley, L Pradhan… - Cell, 2019 - cell.com
Optical interrogation of voltage in deep brain locations with cellular resolution would be
immensely useful for understanding how neuronal circuits process information. Here, we …

Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators

S Chamberland, HH Yang, MM Pan, SW Evans… - elife, 2017 - elifesciences.org
Monitoring voltage dynamics in defined neurons deep in the brain is critical for unraveling
the function of neuronal circuits but is challenging due to the limited performance of existing …

High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor

F St-Pierre, JD Marshall, Y Yang, Y Gong… - Nature …, 2014 - nature.com
Accurate optical reporting of electrical activity in genetically defined neuronal populations is
a long-standing goal in neuroscience. We developed Accelerated Sensor of Action …

High-speed low-light in vivo two-photon voltage imaging of large neuronal populations

J Platisa, X Ye, AM Ahrens, C Liu, IA Chen… - Nature …, 2023 - nature.com
Monitoring spiking activity across large neuronal populations at behaviorally relevant
timescales is critical for understanding neural circuit function. Unlike calcium imaging …

Simultaneous two-photon imaging of action potentials and subthreshold inputs in vivo

Y Bando, M Wenzel, R Yuste - Nature Communications, 2021 - nature.com
To better understand the input-output computations of neuronal populations, we developed
ArcLight-ST, a genetically-encoded voltage indicator, to specifically measure subthreshold …

Fast, in vivo voltage imaging using a red fluorescent indicator

M Kannan, G Vasan, C Huang, S Haziza, JZ Li… - Nature …, 2018 - nature.com
Genetically encoded voltage indicators (GEVIs) are emerging optical tools for acquiring
brain-wide cell-type-specific functional data at unparalleled temporal resolution. To broaden …

A positively tuned voltage indicator for extended electrical recordings in the brain

SW Evans, DQ Shi, M Chavarha, MH Plitt, J Taxidis… - Nature …, 2023 - nature.com
Genetically encoded voltage indicators (GEVIs) enable optical recording of electrical signals
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …

Closed-loop all-optical interrogation of neural circuits in vivo

Z Zhang, LE Russell, AM Packer, OM Gauld… - Nature …, 2018 - nature.com
Understanding the causal relationship between neural activity and behavior requires the
ability to perform rapid and targeted interventions in ongoing activity. Here we describe a …

Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy

Z Liu, X Lu, V Villette, Y Gou, KL Colbert, S Lai, S Guan… - Cell, 2022 - cell.com
Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics
with cell-type specificity. However, current indicators enable a narrow range of applications …

Widefield imaging of rapid pan-cortical voltage dynamics with an indicator evolved for one-photon microscopy

X Lu, Y Wang, Z Liu, Y Gou, D Jaeger… - Nature …, 2023 - nature.com
Widefield imaging with genetically encoded voltage indicators (GEVIs) is a promising
approach for understanding the role of large cortical networks in the neural coding of …