[HTML][HTML] Ultrafast two-photon imaging of a high-gain voltage indicator in awake behaving mice
Optical interrogation of voltage in deep brain locations with cellular resolution would be
immensely useful for understanding how neuronal circuits process information. Here, we …
immensely useful for understanding how neuronal circuits process information. Here, we …
Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators
S Chamberland, HH Yang, MM Pan, SW Evans… - elife, 2017 - elifesciences.org
Monitoring voltage dynamics in defined neurons deep in the brain is critical for unraveling
the function of neuronal circuits but is challenging due to the limited performance of existing …
the function of neuronal circuits but is challenging due to the limited performance of existing …
High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor
Accurate optical reporting of electrical activity in genetically defined neuronal populations is
a long-standing goal in neuroscience. We developed Accelerated Sensor of Action …
a long-standing goal in neuroscience. We developed Accelerated Sensor of Action …
High-speed low-light in vivo two-photon voltage imaging of large neuronal populations
Monitoring spiking activity across large neuronal populations at behaviorally relevant
timescales is critical for understanding neural circuit function. Unlike calcium imaging …
timescales is critical for understanding neural circuit function. Unlike calcium imaging …
Simultaneous two-photon imaging of action potentials and subthreshold inputs in vivo
To better understand the input-output computations of neuronal populations, we developed
ArcLight-ST, a genetically-encoded voltage indicator, to specifically measure subthreshold …
ArcLight-ST, a genetically-encoded voltage indicator, to specifically measure subthreshold …
Fast, in vivo voltage imaging using a red fluorescent indicator
Genetically encoded voltage indicators (GEVIs) are emerging optical tools for acquiring
brain-wide cell-type-specific functional data at unparalleled temporal resolution. To broaden …
brain-wide cell-type-specific functional data at unparalleled temporal resolution. To broaden …
A positively tuned voltage indicator for extended electrical recordings in the brain
Genetically encoded voltage indicators (GEVIs) enable optical recording of electrical signals
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …
Closed-loop all-optical interrogation of neural circuits in vivo
Understanding the causal relationship between neural activity and behavior requires the
ability to perform rapid and targeted interventions in ongoing activity. Here we describe a …
ability to perform rapid and targeted interventions in ongoing activity. Here we describe a …
Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy
Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics
with cell-type specificity. However, current indicators enable a narrow range of applications …
with cell-type specificity. However, current indicators enable a narrow range of applications …
Widefield imaging of rapid pan-cortical voltage dynamics with an indicator evolved for one-photon microscopy
Widefield imaging with genetically encoded voltage indicators (GEVIs) is a promising
approach for understanding the role of large cortical networks in the neural coding of …
approach for understanding the role of large cortical networks in the neural coding of …