Tachykinins and tachykinin receptors: structure and activity relationships
In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide
number of peptides with neurotransmitter activity have been identified in the past few years …
number of peptides with neurotransmitter activity have been identified in the past few years …
The tachykinin NK1 receptor in the brain: pharmacology and putative functions
A Saria - European journal of pharmacology, 1999 - Elsevier
After its discovery in 1931, substance P (SP) remained the only mammalian member of the
family of tachykinin peptides for several decades. Tachykinins thus refer to peptides sharing …
family of tachykinin peptides for several decades. Tachykinins thus refer to peptides sharing …
Tachykinins: receptor to effector
AM Khawaja, DF Rogers - The international journal of biochemistry & cell …, 1996 - Elsevier
Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …
Tachykinins and tachykinin receptors: a growing family
JN Pennefather, A Lecci, ML Candenas, E Patak… - Life sciences, 2004 - Elsevier
The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …
and central nervous systems and play a well-recognized role as excitatory …
Tachykinin receptors and receptor subtypes.
R Patacchini, CA Maggi - Archives internationales de …, 1995 - europepmc.org
The tachykinins, substance P, neurokinin A and neurokinin B, are a family of neuropeptides
widely distributed in the mammalian central and peripheral nervous system. In the …
widely distributed in the mammalian central and peripheral nervous system. In the …
Neurokinin-receptor antagonists: pharmacological tools and therapeutic drugs
J Longmore, RG Hill… - Canadian journal of …, 1997 - cdnsciencepub.com
The mammalian tachykinins (substance P, neurokinin A, and neurokinin B) are widely
distributed throughout the central and peripheral nervous systems, where they act as …
distributed throughout the central and peripheral nervous systems, where they act as …
[引用][C] Nonpeptide antagonists herald new era in tachykinin research
KJ Watling - Trends in pharmacological sciences, 1992 - Elsevier
Throughout the past decade, major advances have been made in our understanding of the
biology of the mammalian tachykinin neuropeptides. It is now well established that …
biology of the mammalian tachykinin neuropeptides. It is now well established that …
Peripheral tachykinin receptors as targets for new drugs
R Patacchini, CA Maggi - European journal of pharmacology, 2001 - Elsevier
Tachykinins are widely distributed in the peripheral nervous system of the respiratory,
urinary and gastrointestinal tract, stored in enteric neurons and in peripheral nerve endings …
urinary and gastrointestinal tract, stored in enteric neurons and in peripheral nerve endings …
Tachykinin receptors: a radioligand binding perspective.
CJ Mussap, DP Geraghty, E Burcher - Journal of neurochemistry, 1993 - europepmc.org
The last decade has witnessed major breakthroughs in the study of tachykinin receptors.
The currently described NK-1, NK-2, and NK-3 receptors have been sequenced and cloned …
The currently described NK-1, NK-2, and NK-3 receptors have been sequenced and cloned …
Biological and pharmacological aspects of the NK1‐receptor
S Garcia-Recio, P Gascón - BioMed research international, 2015 - Wiley Online Library
The neurokinin 1 receptor (NK‐1R) is the main receptor for the tachykinin family of peptides.
Substance P (SP) is the major mammalian ligand and the one with the highest affinity. SP is …
Substance P (SP) is the major mammalian ligand and the one with the highest affinity. SP is …