Recognising and managing antidepressant discontinuation symptoms

PM Haddad, IM Anderson - Advances in Psychiatric Treatment, 2007 - cambridge.org
Antidepressant discontinuation symptoms occur with all classes of antidepressant. A well-
described discontinuation syndrome occurs with the selective serotonin reuptake inhibitors …

Antidepressant discontinuation syndromes: clinical relevance, prevention and management

PM Haddad - Drug Safety, 2001 - Springer
Discontinuation symptoms are recognised with tricyclic antidepressants, monoamine
oxidase inhibitors, selective serotonin reuptake inhibitors (SSRIs) and miscellaneous …

Clinical management of antidepressant discontinuation

JF Rosenbaum, J Zajecka - Journal of Clinical Psychiatry, 1997 - psychiatrist.com
To minimize the symptoms of antidepressant discontinuation, gradual tapering is necessary
for all serotonin reuptake inhibitors (SRIs) except fluoxetine, which has an extended half-life …

Discontinuation symptoms after treatment with serotonin reuptake inhibitors: a literature review

J Zajecka, KA Tracy, S Mitchell - Journal of Clinical Psychiatry, 1997 - psychiatrist.com
Background: The discontinuation of many pharmacologic agents is associated with
characteristic withdrawal symptoms. Antidepressants, particularly the tricyclic …

A review of the management of antidepressant discontinuation symptoms

E Wilson, M Lader - Therapeutic advances in …, 2015 - journals.sagepub.com
Strong evidence supports the existence of a discontinuation syndrome following the
withdrawal of antidepressant medication, particularly second-generation antidepressants …

Steps following attainment of remission: discontinuation of antidepressant therapy

RC Shelton - Primary care companion to the Journal of clinical …, 2001 - psychiatrist.com
Depressive disorders require long-term treatment with antidepressants, psychotherapy, or
both. The goal of antidepressant therapy is complete remission of symptoms and return to …

Antidepressant discontinuation syndrome: consensus panel recommendations for clinical management and additional research

AF Schatzberg, P Blier, PL Delgado… - Journal of Clinical …, 2006 - psychiatrist.com
Objective: Currently, no evidence-based guidelines exist for the management of serotonin
reuptake inhibitor (SRI) discontinuation syndrome. This article summarizes …

Newer antidepressants and the discontinuation syndrome

P Haddad - Journal of Clinical Psychiatry, 1997 - psychiatrist.com
Data on discontinuation phenomena associated with serotonin selective reuptake inhibitors
(SSRIs) are derived primarily from (1) published case reports,(2) data bases of adverse drug …

Antidepressant discontinuation: a review of the literature

M Lejoyeux, J Adès - Journal of Clinical Psychiatry, 1997 - psychiatrist.com
Sudden or tapered withdrawal from treatment with antidepressants, including monoamine
oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), and serotonin selective …

[HTML][HTML] Discontinuing antidepressants: pearls and pitfalls

SJ Zwiebel, AC Viguera - Cleveland Clinic Journal of Medicine, 2022 - ccjm.org
Stopping antidepressants can be challenging due to the high rate of discontinuation
symptoms. Patients with antidepressant discontinuation syndrome (ADS) commonly …