Gut-lung crosstalk in sepsis-induced acute lung injury

X Zhou, Y Liao - Frontiers in microbiology, 2021 - frontiersin.org
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common acute
and severe cases of the respiratory system with complicated pathogenesis and high …

A three-phase approach for the early identification of acute lung injury induced by severe sepsis

T Miyashita, AK Ahmed, S Nakanuma, K Okamoto… - In Vivo, 2016 - iv.iiarjournals.org
A number of studies have reported that acute lung injury (ALI) and acute respiratory distress
syndrome (ARDS) are independent risk factors for organ dysfunction and mortality in …

New insights into the immune molecular regulation of the pathogenesis of acute respiratory distress syndrome

CY Yang, CS Chen, GT Yiang, YL Cheng… - International Journal of …, 2018 - mdpi.com
Acute respiratory distress syndrome is an inflammatory disease characterized by dysfunction
of pulmonary epithelial and capillary endothelial cells, infiltration of alveolar macrophages …

Acute respiratory distress syndrome heterogeneity and the septic ARDS subgroup

H Xu, S Sheng, W Luo, X Xu, Z Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is an acute diffuse inflammatory lung injury
characterized by the damage of alveolar epithelial cells and pulmonary capillary endothelial …

Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury

V Kumar - Frontiers in immunology, 2020 - frontiersin.org
The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …

Infection site is predictive of outcome in acute lung injury associated with severe sepsis and septic shock

S Fujishima, S Gando, S Daizoh, S Kushimoto… - …, 2016 - Wiley Online Library
Background and objective Sepsis is a leading cause of acute lung injury (ALI); however, the
characteristics and outcome of sepsis‐associated ALI are poorly understood. We aimed to …

Pathobiology of sepsis: are we still asking the same questions?

RM Baron, MJ Baron, MA Perrella - American journal of respiratory …, 2006 - atsjournals.org
While the term “sepsis” has been used for centuries to describe critical illness resulting from
infection, a specific definition and conceptual basis for its genesis are still debated (1–3) …

The value of the lipopolysaccharide-induced acute lung injury model in respiratory medicine

H Chen, C Bai, X Wang - Expert review of respiratory medicine, 2010 - Taylor & Francis
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a syndrome
characterized by pulmonary edema and acute inflammation. Lipopolysaccharide (LPS), a …

Gene expression profiles characterize inflammation stages in the acute lung injury in mice

I Lesur, J Textoris, B Loriod, C Courbon, S Garcia… - PLoS …, 2010 - journals.plos.org
Acute Lung Injury (ALI) carries about 50 percent mortality and is frequently associated with
an infection (sepsis). Life-support treatment with mechanical ventilation rescues many …

Pulmonary vs nonpulmonary sepsis and mortality in acute lung injury

JE Sevransky, GS Martin, P Mendez-Tellez… - Chest, 2008 - Elsevier
Background Acute lung injury (ALI) is a frequent complication of sepsis. It is unclear if a
pulmonary vs nonpulmonary source of sepsis affects mortality in patients with sepsis …