Amiodarone hepatotoxicity: prevalence and clinicopathologic correlations among 104 patients

JH Lewis, RC Ranard, A Caruso, LK Jackson… - Hepatology, 1989 - journals.lww.com
The prevalence of apparent amiodarone-related hepatic injury in 104 patients followed
prospectively is compared to that reported in the literature. Asymptomatic elevation of serum …

Amiodarone hepatotoxicity

M Babatin, SS Lee, PT Pollak - Current vascular pharmacology, 2008 - ingentaconnect.com
Potential hepatotoxicity related to amiodarone therapy is often a concern when deciding
whether to initiate or continue treatment with this medication. While mostly associated with …

Histopathologic analysis of suspected amiodarone hepatotoxicity

JH Lewis, F Mullick, KG Ishak, RC Ranard, B Ragsdale… - Human pathology, 1990 - Elsevier
This analysis of the morphology of suspected amiodarone (AD) liver disease is based on a
study of liver specimens from 17 individuals. Changes similar to alcoholic liver injury were …

Amiodarone hepatotoxicity: a clinicopathologic study of five patients

B RIGAS, LE ROSENFELD, KW BARWICK… - Annals of Internal …, 1986 - acpjournals.org
Five patients had amiodarone hepatotoxicity detected on routine biochemical monitoring.
Symptoms attributable to hepatotoxicity were minimal or absent; reversible hepatomegaly …

Severe intrahepatic cholestasis caused by amiodarone toxicity after withdrawal of the drug: a case report and review of the literature

CC Chang, M Petrelli… - … of Pathology and …, 1999 - meridian.allenpress.com
Cholestasis has been reported as a rare presentation among patients with severe liver injury
secondary to amiodarone hepatic toxicity. We report an unusual case of amiodarone …

Amiodarone hepatotoxicity simulating alcoholic liver disease

JB Simon, PN Manley, JF Brien… - New England Journal …, 1984 - Mass Medical Soc
AMIODARONE, an iodine-containing benzofuran derivative, has been widely available in
Europe for over 15 years, but its use in North America is still experimental. The drug has …

Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives

KM Waldhauser, M Török, HR Ha, U Thomet… - Journal of pharmacology …, 2006 - ASPET
The aim of this work was to compare hepatocellular toxicity and pharmacological activity of
amiodarone (2-n-butyl-3-[3, 5 diiodo-4-diethylaminoethoxybenzoyl]-benzofuran; B2-O-Et-N …

Early acute hepatitis with parenteral amiodarone: a toxic effect of the vehicle?

A Rhodes, JB Eastwood, SA Smith - Gut, 1993 - gut.bmj.com
A 72 year old white man developed acute hepatic impairment and renal failure within 24
hours of starting intravenous amiodarone for paroxysmal ventricular tachycardia. After …

Increased hepatic density and phospholipidosis due to amiodarone

IS Goldman, ML Winkler, SE Raper… - American journal of …, 1985 - Am Roentgen Ray Soc
Amiodarone is an amphiphilic iodinated compound that is used as a treatment for refractory
ventricular arrhythmias. During evaluation for possible pulmonary toxicity, a patient receiving …

[PDF][PDF] Amiodarone‐induced hepatic phospholipidosis: a morphological alteration independent of pseudoalcoholic liver disease

B Guigui, S Perrot, JP Berry, J Fleury‐Feith… - …, 1988 - Wiley Online Library
In order to study the relationship between amiodarone‐induced hepatic phospholipidosis
and liver disease, liver biopsies obtained from 13 patients treated with amiodarone for 4 …