The physical basis of ventilator-induced lung injury
M Plataki, RD Hubmayr - Expert review of respiratory medicine, 2010 - Taylor & Francis
Although mechanical ventilation (MV) is a life-saving intervention for patients with acute
respiratory distress syndrome (ARDS), it can aggravate or cause lung injury, known as …
respiratory distress syndrome (ARDS), it can aggravate or cause lung injury, known as …
[HTML][HTML] Ventilator-induced lung injury: historical perspectives and clinical implications
N De Prost, JD Ricard, G Saumon, D Dreyfuss - Annals of intensive care, 2011 - Springer
Mechanical ventilation can produce lung physiological and morphological alterations
termed ventilator-induced lung injury (VILI). Early experimental studies demonstrated that …
termed ventilator-induced lung injury (VILI). Early experimental studies demonstrated that …
Invited review: mechanisms of ventilator-induced lung injury: a perspective
CC Dos Santos, AS Slutsky - Journal of applied physiology, 2000 - journals.physiology.org
Despite advances in critical care, the mortality rate in patients with acute lung injury remains
high. Furthermore, most patients who die do so from multisystem organ failure. It has been …
high. Furthermore, most patients who die do so from multisystem organ failure. It has been …
[HTML][HTML] Lung stress, strain, and energy load: engineering concepts to understand the mechanism of ventilator-induced lung injury (VILI)
GF Nieman, J Satalin, P Andrews, NM Habashi… - Intensive care medicine …, 2016 - Springer
It was recently shown that acute respiratory distress syndrome (ARDS) mortality has not
been reduced in over 15 years and remains~ 40%, even with protective low tidal volume …
been reduced in over 15 years and remains~ 40%, even with protective low tidal volume …
Ventilator-induced lung injury during controlled ventilation in patients with acute respiratory distress syndrome: less is probably better
Introduction: Mechanical ventilation is required to support respiratory function in the acute
respiratory distress syndrome (ARDS), but it may promote lung damage, a phenomenon …
respiratory distress syndrome (ARDS), but it may promote lung damage, a phenomenon …
Pathogenesis of ventilator-induced lung injury: trials and tribulations
LN Tremblay, AS Slutsky - American Journal of Physiology …, 2005 - journals.physiology.org
RESEARCH INTO VENTILATOR-INDUCED LUNG INJURY (VILI) spans the decades since
this life-sustaining technology was introduced into widespread clinical use in the mid …
this life-sustaining technology was introduced into widespread clinical use in the mid …
[HTML][HTML] Ventilator-induced lung injury and lung mechanics
Mechanical ventilation applies physical stresses to the tissues of the lung and thus may give
rise to ventilator-induced lung injury (VILI), particular in patients with acute respiratory …
rise to ventilator-induced lung injury (VILI), particular in patients with acute respiratory …
Biotrauma and ventilator-induced lung injury: clinical implications
The pathophysiological mechanisms by which mechanical ventilation can contribute to lung
injury, termed “ventilator-induced lung injury”(VILI), is increasingly well understood.“ …
injury, termed “ventilator-induced lung injury”(VILI), is increasingly well understood.“ …
How respiratory system mechanics may help in minimising ventilator-induced lung injury in ARDS patients
PP Terragni, GL Rosboch, A Lisi… - European …, 2003 - Eur Respiratory Soc
The main supportive therapy in acute respiratory distress syndrome patients is mechanical
ventilation. As with any therapy, mechanical ventilation has side-effects, and may induce …
ventilation. As with any therapy, mechanical ventilation has side-effects, and may induce …
Mechanisms of ventilator-induced lung injury in healthy lungs
Mechanical ventilation is an essential method of patient support, but it may induce lung
damage, leading to ventilator-induced lung injury (VILI). VILI is the result of a complex …
damage, leading to ventilator-induced lung injury (VILI). VILI is the result of a complex …