Microglia as a source and target of cytokines
UK Hanisch - Glia, 2002 - Wiley Online Library
Cytokines constitute a significant portion of the immuno‐and neuromodulatory messengers
that can be released by activated microglia. By virtue of potent effects on resident and …
that can be released by activated microglia. By virtue of potent effects on resident and …
Microglia biology in health and disease
GA Garden, T Möller - Journal of Neuroimmune Pharmacology, 2006 - Springer
Microglia cells are resident central nervous system (CNS) leukocytes that regulate innate
immunity and participate in adaptive immune responses in CNS tissue. However, microglia …
immunity and participate in adaptive immune responses in CNS tissue. However, microglia …
Neurotransmitter receptors on microglia
JM Pocock, H Kettenmann - Trends in neurosciences, 2007 - cell.com
Microglia are the intrinsic immune cells of the brain and express chemokine and cytokine
receptors that interact with the peripheral immune cells. Recent studies have indicated that …
receptors that interact with the peripheral immune cells. Recent studies have indicated that …
Role of microglia in neurological disorders and their potentials as a therapeutic target
L Du, Y Zhang, Y Chen, J Zhu, Y Yang… - Molecular neurobiology, 2017 - Springer
Microglia are resident macrophage-like immune cells in the central nervous system (CNS)
and play a vital role in both physiological and pathological conditions, including restoring …
and play a vital role in both physiological and pathological conditions, including restoring …
Microglia: key innate immune cells of the brain
J Kofler, CA Wiley - Toxicologic pathology, 2011 - journals.sagepub.com
Microglia are the histiocytes of the central nervous system. These long-lived cells undergo
very little turnover in normal physiological states; however, in pathological conditions …
very little turnover in normal physiological states; however, in pathological conditions …
Microglial physiology: unique stimuli, specialized responses
RM Ransohoff, VH Perry - Annual review of immunology, 2009 - annualreviews.org
Microglia, the macrophages of the central nervous system parenchyma, have in the normal
healthy brain a distinct phenotype induced by molecules expressed on or secreted by …
healthy brain a distinct phenotype induced by molecules expressed on or secreted by …
Physiology of microglia
H Kettenmann, UK Hanisch, M Noda… - Physiological …, 2011 - journals.physiology.org
Microglial cells are the resident macrophages in the central nervous system. These cells of
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …
Microglia
D van Rossum, UK Hanisch - Metabolic brain disease, 2004 - Springer
Microglia—the macrophage equivalent of the CNS—safeguards and supports neuronal
functions. Threats to the CNS homeostasis can trigger a rapid transformation of these cells …
functions. Threats to the CNS homeostasis can trigger a rapid transformation of these cells …
[HTML][HTML] Microglia: a sensor for pathological events in the CNS
GW Kreutzberg - Trends in neurosciences, 1996 - cell.com
The most characteristic feature of microglial cells is their rapid activation in response to even
minor pathological changes in the CNS. Microglia activation is a key factor in the defence of …
minor pathological changes in the CNS. Microglia activation is a key factor in the defence of …
Role of microglia in neuronal degeneration and regeneration
Microglial cells, the resident macrophage population of the central nervous system (CNS),
actively scan tissue under both normal and pathologic contexts. Their resulting engagement …
actively scan tissue under both normal and pathologic contexts. Their resulting engagement …